Abeta Peptide and Alzheimer’s Disease

Celebrating a Century of Research

  • Colin J. Barrow
  • David H. Small

Table of contents

  1. Front Matter
    Pages i-xi
  2. Victor L. Villemagne, Roberto Cappai, Kevin J. Barnham, Robert A. Cherny, Carlos Opazo, Kathy E. Novakovic et al.
    Pages 5-36
  3. Roberto Cappai, B. Elise Needham, Giuseppe D. Ciccotosto
    Pages 37-51
  4. Piet Eikelenboom, Willem A. van Gool, Annemieke J. M. Rozemuller, Wiep Scheper, Rob Veerhuis, Jeroen J. M. Hoozemans
    Pages 52-82
  5. Joanna M. Cordy, Benjamin Wolozin
    Pages 142-158
  6. Satyabrata Karn, Z. Wei, David MacTavish, Doreen Kabogo, Mee-Sook Song, Jack H. Jhamandas
    Pages 159-178
  7. Gillian C. Gregory, Claire E. Shepherd, Glenda M. Halliday
    Pages 179-197
  8. Jürgen Götz, Della C. David, Lars M. Ittner
    Pages 198-215
  9. Gilbert Siu, Peter Clifford, Mary Kosciuk, Venkat Venkataraman, Robert G. Nagele
    Pages 216-233
  10. Dwight C. German
    Pages 259-273
  11. Back Matter
    Pages 274-298

About this book

Introduction

Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.

Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases, such as prion disease, Parkinson’s and Huntington’s.

This book will primarily be of interest to AD researchers and clinicians but also to researchers of other amyloid diseases.

Keywords

Alzheimer alzheimer's disease amyloid precursor protein biochemistry brain cell death chemistry death genetics inflammation neuropathology oxidative stress pathology protein tissue

Editors and affiliations

  • Colin J. Barrow
    • 1
  • David H. Small
    • 2
  1. 1.Research and DevelopmentOcean Nutrition CanadaDartmouthCanada
  2. 2.Department of Biochemistry and Molecular BiologyMonash UniversityClaytonAustralia

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-84628-440-3
  • Copyright Information Springer-Verlag London Limited 2007
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-85233-961-6
  • Online ISBN 978-1-84628-440-3
  • About this book