Book Volume 1055 2013

Metabolomics Tools for Natural Product Discovery

Methods and Protocols

Editors:

ISBN: 978-1-62703-576-7 (Print) 978-1-62703-577-4 (Online)

Table of contents (20 protocols)

  1. Front Matter

    Pages i-x

  2. No Access

    Protocol

    Pages 1-20

    Bryophytes: Liverworts, Mosses, and Hornworts: Extraction and Isolation Procedures

  3. No Access

    Protocol

    Pages 21-28

    Plant Tissue Extraction for Metabolomics

  4. No Access

    Protocol

    Pages 29-37

    Detection of Polar Metabolites Through the Use of Gas Chromatography–Mass Spectrometry

  5. No Access

    Protocol

    Pages 39-56

    A Robust GC-MS Method for the Quantitation of Fatty Acids in Biological Systems

  6. No Access

    Protocol

    Pages 57-70

    A Workflow from Untargeted LC-MS Profiling to Targeted Natural Product Isolation

  7. No Access

    Protocol

    Pages 71-80

    Lipidomics: Extraction Protocols for Biological Matrices

  8. No Access

    Protocol

    Pages 81-97

    Metabolite Analysis of Biological Fluids and Tissues by Proton Nuclear Magnetic Resonance Spectroscopy

  9. No Access

    Protocol

    Pages 99-116

    NMR Spectroscopy: Structure Elucidation of Cycloelatanene A: A Natural Product Case Study

  10. No Access

    Protocol

    Pages 117-127

    NMR-Based Metabolomics: A Probe to Utilize Biodiversity

  11. No Access

    Protocol

    Pages 129-147

    Extraction Protocol for Nontargeted NMR and LC-MS Metabolomics-Based Analysis of Hard Coral and Their Algal Symbionts

  12. No Access

    Protocol

    Pages 149-162

    Determination of Absolute Configuration Using Single Crystal X-Ray Diffraction

  13. No Access

    Protocol

    Pages 163-170

    Natural Product Chemistry in Action: The Synthesis of Melatonin Metabolites K1 and K2

  14. No Access

    Protocol

    Pages 171-189

    Discovery, Biosynthesis, and Rational Engineering of Novel Enterocin and Wailupemycin Polyketide Analogues

  15. No Access

    Protocol

    Pages 191-205

    Bioassays for Anticancer Activities

  16. No Access

    Protocol

    Pages 207-218

    Screening for Antidiabetic Activities

  17. No Access

    Protocol

    Pages 219-225

    Screening for Antibacterial, Antifungal, and Anti quorum Sensing Activity

  18. No Access

    Protocol

    Pages 227-244

    Metabolomics and Dereplication Strategies in Natural Products

  19. No Access

    Protocol

    Pages 245-266

    Bridging the Gap: Basic Metabolomics Methods for Natural Product Chemistry

  20. No Access

    Protocol

    Pages 267-289

    Strategies in Biomarker Discovery. Peak Annotation by MS and Targeted LC-MS Micro-Fractionation for De Novo Structure Identification by Micro-NMR

  21. No Access

    Protocol

    Pages 291-307

    Statistical Analysis of Metabolomics Data

  22. Back Matter

    Pages 309-311