New Advances on Disease Biomarkers and Molecular Targets in Biomedicine

  • Nikki P. Lee
  • C.Y. Cheng
  • John M. Luk

Table of contents

  1. Front Matter
    Pages i-xii
  2. Xiang Xiao, Dolores D. Mruk, Pranitha Jenardhanan, Jayakanthan Mannu, Premendu P. Mathur, Will M. Lee et al.
    Pages 1-25
  3. Kwong-Fai Wong, Xiaoou Jiang, John M. Luk
    Pages 39-56
  4. Felix H. Shek, Tracy C. W. Lai, Sarwat Fatima, Nikki P. Lee
    Pages 57-74
  5. Nelson S. Yee, Rosemary K. Yee
    Pages 75-84
  6. Kenneth K. Lai, Kin-Tak Chan, Sarwat Fatima, Nikki P. Lee, Simon Law
    Pages 85-103
  7. Renu Wadhwa, Rumani Singh, Zeenia Kaul, Sunil C. Kaul
    Pages 137-157
  8. Angela M. Liu, Wei Wang, John M. Luk
    Pages 159-174
  9. Jianzhou Cui, Han-Ming Shen
    Pages 175-203
  10. Shengtao Zhou, Manchao Kuang, Xia Zhao, Canhua Huang
    Pages 205-216
  11. Qian Liu, Weiliang Xia
    Pages 231-242
  12. Stella Sun, Derek Lee, Gilberto K. K. Leung
    Pages 243-270
  13. Back Matter
    Pages 271-275

About this book

Introduction

Rising occurrences of various diseases and epidemics have pressurized the already-burdened health system across the globe, and this imposes an unprecedented challenge on our current research in identifying disease-specific biomarkers and molecular targets, in particular for cancers, neurological disorders and unexplained infertility. Despite decades of efforts in deciphering the fundamental biology underlying various diseases at discrete levels using an array of advanced technologies, attempts to identify reliable and disease-indicating markers for detection and biomolecules or cellular structures for targeting are still in vain. This monograph describes and discusses the updated findings in this field with a specific aim to compile prior and recent literature and from there to acquire some insights to facilitate future research to expand our options of understanding, detecting and treating diseases. Among the many possible areas of biomedical research, this content comprises two themes: disease biomarkers and molecular targets. We also cover topics that are more advanced in development to emerging scientific discoveries. In particular, we have included in this monograph concepts on the renovated use of oncofetal molecules in cancer prediction and treatment, the evolving development in cancer biology at the cellular and molecular levels and the recent involvement on new classes of molecules in diseases. We hope that this book can renew established concepts in the field, and at the same time lead to important insights for research and development of drugs, diagnostics, and interventions for managing diseases of unmet medical needs.

Keywords

Biomarkers Biomedicine Lee Molecular Target

Editors and affiliations

  • Nikki P. Lee
    • 1
  • C.Y. Cheng
    • 2
  • John M. Luk
    • 3
  1. 1.Faculty of Medicine Building, Department of SurgeryUniversity of Hong KongHong KongHong Kong SAR
  2. 2.Center for Biomedical ResearchPopulation CouncilNEW YORKUSA
  3. 3.Yong Loo Lin School of Medicine, Department of Pharmacology and DepartmenNational University of SingaporeSingaporeSingapore

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-62703-456-2
  • Copyright Information Springer Science+Business Media New York 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-62703-455-5
  • Online ISBN 978-1-62703-456-2
  • About this book