Microelectrode Biosensors

  • Stéphane Marinesco
  • Nicholas Dale

Part of the Neuromethods book series (NM, volume 80)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Designs, Principles, and Methods

    1. Front Matter
      Pages 1-1
    2. Stéphane Marinesco, Olivier Frey
      Pages 3-25
    3. Kevin N. Hascup, Erin R. Hascup, O. Meagan Littrell, Jason M. Hinzman, Catherine E. Werner, Verda A. Davis et al.
      Pages 27-54
    4. Faming Tian, Nicholas Dale
      Pages 69-93
    5. Natalia Vasylieva, Stéphane Marinesco
      Pages 95-114
  3. Case Studies

    1. Front Matter
      Pages 151-151
    2. Si Qin, Miranda (van der Zeyden) Evering, Ngabi Wahono, Thomas I. F. H. Cremers, Ben H. C. Westerink
      Pages 153-177
    3. Erin R. Hascup, Kevin N. Hascup, Pooja M. Talauliker, David A. Price, Francois Pomerleau, Jorge E. Quintero et al.
      Pages 179-199
    4. Raymond Cespuglio, Larissa Netchiporouk, Nataliya Shram
      Pages 241-256
  4. The Future?

    1. Front Matter
      Pages 279-279
    2. Paloma Yáñez-Sedeño, Lourdes Agüí, José M. Pingarrón
      Pages 281-294
    3. Robert J. Forster, Tia E. Keyes
      Pages 347-367
    4. Yi Ge, Samir Akhtar, Farhan Mirza, Sergey Piletsky, Shenqi Wang, Dan Fei
      Pages 369-384
  5. Back Matter
    Pages 385-387

About this book


For molecules that are not directly electroactive, it is necessary to modify a microelectrode by grafting polymeric or enzymatic membranes capable of translating a local concentration into an electrical current, which is a concept referred to as biosensing. In Microelectrode Biosensors, experts in the field cover the topic of electrochemical biosensor technology as applied to the neurosciences.  The volume opens with a section addressing the specific issue of manufacturing biosensors that can be implanted in the central nervous system for neurotransmitter detection, and it then continues with sections on recent studies where biosensors have made a difference in bringing a new level of understanding of signaling mechanisms in neuroscience as well as recent developments in biosensor technology that have not yet been applied to implantable microelectrodes but may have great potential. Written for the Neuromethods series, this work contains the kind of detailed descriptions and implementation advice necessary to achieve successful results.


Focused and cutting-edge, Microelectrode Biosensors serves to inspire the wider neuroscience and physiology community to adopt these powerful methods in their own applications in order to move the field forward with the widespread advances that will most likely flow from the adoption of biosensing as part of the standard laboratory toolkit.


Biosensing Electrochemical biosensor Implantable microelectrodes Neurotransmitters Signaling mechanisms

Editors and affiliations

  • Stéphane Marinesco
    • 1
  • Nicholas Dale
    • 2
  1. 1.Faculté de médecine, CRNLUniversité Claude Bernard Lyon ILyonFrance
  2. 2.School of Life SciencesUniversity of WarwickCoventryUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-369-5
  • Online ISBN 978-1-62703-370-1
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site