Stem Cells and Aging

Methods and Protocols

  • Kursad Turksen

Part of the Methods in Molecular Biology book series (MIMB, volume 976)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Kyle Rector, Yi Liu, Gary Van Zant
    Pages 1-15
  3. Hui Cheng, Paulina H. Liang, Tao Cheng
    Pages 25-35
  4. Mladen I. Yovchev, Mariana D. Dabeva, Michael Oertel
    Pages 37-51
  5. Mitra Lavasani, Aiping Lu, Seth D. Thompson, Paul D. Robbins, Johnny Huard, Laura J. Niedernhofer
    Pages 53-65
  6. Manuela Malatesta, Marzia Giagnacovo, Rosanna Cardani, Giovanni Meola, Carlo Pellicciari
    Pages 67-79
  7. Daniela Cesselli, Federica D’Aurizio, Patrizia Marcon, Natascha Bergamin, Carlo Alberto Beltrami, Antonio Paolo Beltrami
    Pages 81-97
  8. Sebastian Klepsch, Angelika Jamnig, Daniela Trimmel, Magdalena Schimke, Werner Kapferer, Regina Brunauer et al.
    Pages 99-109
  9. Sindhu T. Mohanty, Ilaria Bellantuono
    Pages 131-141
  10. Anne Schellenberg, Hatim Hemeda, Wolfgang Wagner
    Pages 143-154
  11. Mario Ricciardi, Mauro Krampera, Marco Chilosi
    Pages 167-173
  12. Back Matter
    Pages 175-179

About this book


Over time, it has become clear that changes in stem cells do occur during aging, not only in their number but also in their relationship to their microenvironment and their functionality as reflected in changes to their metabolome.  Stem Cells and Aging: Methods and Protocols brings together chapters from expert contributors with protocols critical for exploring the biology of stem cell aging, all of which is key for understanding these age-related stem cell changes at a basic biology level and at the level of their impacts for regenerative medicine.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.


Concise and easy to use, Stem Cells and Aging: Methods and Protocols serves as an ideal reference to guide investigators toward further valuable answers to the problems of our aging population.


Aging Functionality changes Regenerative medicine Stem cell biology The metabolome

Editors and affiliations

  • Kursad Turksen
    • 1
  1. 1.Sprott Centre for Stem Cell Research, Regenerative Medicine ProgramOttawa Hospital Research InstituteOttawaCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-316-9
  • Online ISBN 978-1-62703-317-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site