Animal Models of Brain Tumors

  • Ricardo Martínez Murillo
  • Alfredo Martínez

Part of the Neuromethods book series (NM, volume 77)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Thomas N. Seyfried, Laura M. Shelton, Leanne C. Huysentruyt
    Pages 39-55
  3. Nanna Lindberg, Lene Uhrbom
    Pages 57-82
  4. Jasmine Lau, William A. Weiss
    Pages 83-140
  5. Jesús Vaquero, Mercedes Zurita
    Pages 153-161
  6. Jessica Rainey, Randy L. Jensen
    Pages 163-173
  7. Walavan Sivakumar, William T. Couldwell
    Pages 175-179
  8. Kelly Burrell, Elena Bogdanovic, Shahrzad Jalali, Abhijit Guha, Gelareh Zadeh
    Pages 181-200
  9. Julie Lessard, Al Charest
    Pages 217-225
  10. Hikmat Assi, Marianela Candolfi, Pedro R. Lowenstein, Maria G. Castro
    Pages 229-243
  11. Kristen A. Batich, Bryan D. Choi, Duane A. Mitchell
    Pages 245-273
  12. Stephen M. Robbins, Donna L. Senger
    Pages 275-298
  13. Yannic Waerzeggers, Thomas Viel, Sonja Schäfers, Stefan Wagner, Andreas Faust, Burkhard Riemann et al.
    Pages 301-327
  14. André Constantinesco, Christian Goetz, Philippe Choquet
    Pages 367-382
  15. Back Matter
    Pages 383-391

About this book


Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis.  Animal Models of Brain Tumors brings together developments and discoveries in “in vivo” experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors,  therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism.  Written for the popular Neuromethods series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results.


Authoritative and cutting-edge, Animal Models of Brain Tumors provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments.


Brain neoplasms Experimental neuro-oncology Imaging technologies Malignant glioma therapies Oncogenesis Tumor biology

Editors and affiliations

  • Ricardo Martínez Murillo
    • 1
  • Alfredo Martínez
    • 2
  1. 1.Instituto Cajal, Molecular, Cellular & Developmental NeurCSICMadridSpain
  2. la Rioja (CIBIR), Oncology AreaCentro de Investigación BiomédicaLogroñoSpain

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-208-7
  • Online ISBN 978-1-62703-209-4
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site