Microdialysis Techniques in Neuroscience

  • Giuseppe Di Giovanni
  • Vincenzo Di Matteo

Part of the Neuromethods book series (NM, volume 75)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Giuseppe Di Giovanni, Massimo Pierucci, Mauro Pessia, Vincenzo Di Matteo
    Pages 23-42
  3. Christian Höcht, Facundo Martín Bertera, Carlos Alberto Taira
    Pages 43-61
  4. Cheng-fu Chen, Brian T. Rasley, Benjamin P. E. Warlick, Tom K. Green, Kristian E. Swearingen, Kelly L. Drew
    Pages 63-88
  5. H. Ronald Zielke, Carol L. Zielke, Peter J. Baab
    Pages 89-102
  6. Teodoro Zornoza, María José Cano-Cebrián, Ana Polache, Luis Granero
    Pages 103-120
  7. Vincent Umbrain, Lin Shi, Jan Poelaert, Ilse Smolders
    Pages 157-174
  8. Salvatore Galati, Giuseppe Di Giovanni
    Pages 209-223
  9. Maria Alessandra Colivicchi, Chiara Stefanini, Wolfhardt Freinbichler, Chiara Ballini, Loria Bianchi, Keith F. Tipton et al.
    Pages 225-247
  10. Omar S. Mabrouk, Robert T. Kennedy
    Pages 249-259
  11. Neil D. Hershey, Robert T. Kennedy
    Pages 261-273
  12. Back Matter
    Pages 339-341

About this book


Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book’s contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice.


Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications.


Brain function Energy metabolism Extrasynaptic pools Microdialysis Neuromodulators Neuronal circuit pathology Neurotransmitters Pharmacokinetics Reverse microdialysis

Editors and affiliations

  • Giuseppe Di Giovanni
    • 1
  • Vincenzo Di Matteo
    • 2
  1. 1., Dept. of Physiology & BiochemistryUniversity of MaltaMsida MSDMalta
  2. 2.Consorzio "Mario Negri" SudSanta Maria ImbaroItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-172-1
  • Online ISBN 978-1-62703-173-8
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site