© 2012

TRP Channels in Drug Discovery

Volume II

  • Arpad Szallasi
  • Tamás Bíró

Part of the Methods in Pharmacology and Toxicology book series (MIPT)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. TRPs and Cardiovascular Disease

    1. Front Matter
      Pages 1-1
    2. José C. González-Cobos, Xuexin Zhang, Rajender K. Motiani, Kelly E. Harmon, Mohamed Trebak
      Pages 3-40
    3. Xiaojing Sun, Xiaolei Xu
      Pages 41-54
    4. Luciana Aparecida Campos, Ovidiu Constantin Baltatu
      Pages 91-99
  3. TRPs and the Brain

    1. Front Matter
      Pages 113-113
    2. Antonio Reboreda
      Pages 115-140
    3. Caitlin J. Riebe, Carsten T. Wotjak
      Pages 167-185
    4. Jennifer L. McGuire, Jennifer L. Coyner, Luke R. Johnson
      Pages 187-202
    5. Stephen W. White, Kenneth J. Sufka
      Pages 203-210
    6. Ryan C. Turner, Alisa S. Elliott, Jason D. Huber, Charles L. Rosen
      Pages 211-229
    7. Robert J. Gasperini, Lisa Foa
      Pages 239-252
  4. TRPs and Skin

    1. Front Matter
      Pages 253-253
    2. Heike Benecke, Janine Wäring, Tobias Lotts, Sonja Ständer
      Pages 255-277

About this book


Recent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention.  TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field.  Volume II presents practical methodologies involving models for disorders of the cardiovascular system, the brain, skin, the metabolic system, as well as colitis, cancer, thermosensation, and musculoskeletal disorders.  Written for the Methods in Pharmacology and Toxicology™ series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab.


Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.


Brain disorders Cardiovascular disease Drug discovery Ion channels Metabolic disorders Pharmaceuticals Preclinical development TRP channelopathies Transient Receptor Potential channels

Editors and affiliations

  • Arpad Szallasi
    • 1
  • Tamás Bíró
    • 2
  1. 1.Transfusion ServicesMonmouth Medical CenterLong BranchUSA
  2. 2.Department of PhysiologyUniversity of Debrecen Medical and Health Science CenterDebrecenHungary

Bibliographic information

  • Book Title TRP Channels in Drug Discovery
  • Book Subtitle Volume II
  • Editors Arpad Szallasi
    Tamás Bíró
  • Series Title Methods in Pharmacology and Toxicology
  • Series Abbreviated Title Meth.Pharmacology,Toxicology
  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-1-62703-094-6
  • Softcover ISBN 978-1-4939-6066-8
  • eBook ISBN 978-1-62703-095-3
  • Series ISSN 1557-2153
  • Series E-ISSN 1940-6053
  • Edition Number 1
  • Number of Pages XIV, 489
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pharmacology/Toxicology
  • Buy this book on publisher's site