Retinal Degeneration

Methods and Protocols

  • Bernhard H.F. Weber

Part of the Methods in Molecular Biology book series (MIMB, volume 935)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Human Genetics

    1. Front Matter
      Pages 1-1
    2. Kornelia Neveling, Anneke I. den Hollander, Frans P. M. Cremers, Rob W. J. Collin
      Pages 3-23
  3. Mouse Models

    1. Front Matter
      Pages 25-25
    2. Anne F. Alex, Peter Heiduschka, Nicole Eter
      Pages 41-67
    3. Naoyuki Tanimoto, Vithiyanjali Sothilingam, Mathias W. Seeliger
      Pages 69-78
    4. M. Dominik Fischer, Ahmad Zhour, Christoph J. Kernstock
      Pages 79-85
    5. Christian Grimm, Charlotte E. Remé
      Pages 87-97
  4. Other Animal Models

    1. Front Matter
      Pages 111-111
    2. Beatrice M. Tam, Christine C.-L. Lai, Zusheng Zong, Orson L. Moritz
      Pages 113-125
    3. Holger Dill, Bastian Linder, Anja Hirmer, Utz Fischer
      Pages 127-137
    4. Sabina P. Huber-Reggi, Kaspar P. Mueller, Stephan C. F. Neuhauss
      Pages 139-160
  5. In Situ Analyses

    1. Front Matter
      Pages 183-183
    2. Christiana L. Cheng, Hidayat Djajadi, Robert S. Molday
      Pages 185-199
    3. Ryosuke Enoki, Amane Koizumi
      Pages 201-205
    4. Francesca Doonan, Thomas G. Cotter
      Pages 207-213
  6. Tissue Culture and Cell Models

    1. Front Matter
      Pages 255-255
    2. Antje Wurm, Thomas Pannicke, Andreas Reichenbach
      Pages 257-270
    3. Debra A. Carter, Balini Balasubramaniam, Andrew D. Dick
      Pages 271-283
  7. Gene Regulation

    1. Front Matter
      Pages 309-309
    2. Cynthia L. Montana, Connie A. Myers, Joseph C. Corbo
      Pages 329-340
  8. Therapy

    1. Front Matter
      Pages 341-341
    2. Regine Mühlfriedel, Stylianos Michalakis, Marina Garcia Garrido, Martin Biel, Mathias W. Seeliger
      Pages 343-349
    3. Matthew Campbell, Marian M. Humphries, Peter Humphries
      Pages 371-380
  9. Back Matter
    Pages 381-384

About this book


Over the past decades, knowledge about the cellular and molecular basis underlying the visual process has remarkably increased. In Retinal Degeneration: Methods and Protocols, expert researchers in the field provide a guide of relevant and state-of-the-art methods for studying retinal homeostasis and disease. These include methods and techniques for addressing cell culture systems and animal models of disease, their generation, their phenotypic and molecular characterization as well as their use in therapeutic approaches to the retina. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Retinal Degeneration: Methods and Protocols aids scientists in continuing to study the  cutting-edge techniques of retinal cell biology in health and disease.


adeno-associated viral vectors animal models of disease cell culture systems gene regulation homoeostatic processes in situ retina retinal degeneration retinal disease subretinal injection

Editors and affiliations

  • Bernhard H.F. Weber
    • 1
    • 2
  1. 1., Institute of Human GeneticsUniversity of RegensburgRegensburgGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-079-3
  • Online ISBN 978-1-62703-080-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site