Animal Models in Diabetes Research

  • Hans-Georg Joost
  • Hadi Al-Hasani
  • Annette Schürmann

Part of the Methods in Molecular Biology book series (MIMB, volume 933)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Rodent Models of Type 1 Diabetes

    1. Front Matter
      Pages 1-1
    2. Kritika Kachapati, David Adams, Kyle Bednar, William M. Ridgway
      Pages 3-16
    3. Jae-Hyung Chang, Susan B. Gurley
      Pages 17-29
    4. Rita Bortell, Chaoxing Yang
      Pages 31-44
  3. Rodent Models of Type 2 Diabetes

    1. Front Matter
      Pages 45-45
    2. Reinhart Kluge, Stephan Scherneck, Annette Schürmann, Hans-Georg Joost
      Pages 59-73
    3. Jung Han Kim, Arnold M. Saxton
      Pages 75-87
    4. Nurit Kaiser, Erol Cerasi, Gil Leibowitz
      Pages 89-102
    5. Masakazu Shiota, Richard L. Printz
      Pages 103-123
    6. Bernard Portha, Marie-Hélène Giroix, Cecile Tourrel-Cuzin, Hervé Le-Stunff, Jamileh Movassat
      Pages 125-159
    7. Md. Shahidul Islam, Rachel Dorothy Wilson
      Pages 161-174
  4. Other Species

    1. Front Matter
      Pages 175-175
  5. General Methodology

About this book

Introduction

In recent years, human studies have made enormous contributions towards an understanding of the genetic basis of diabetes mellitus; however, most of the experimentation needed for the invention and testing of novel therapeutic approaches cannot be performed in humans.  Thus, there is no alternative to appropriate animal models.  In Animal Models in Diabetes Research, expert researchers explore the current status of the most important models and procedures in order to provide a timely resource in experimental diabetology.  The first half of the volume serves as a comprehensive overview on our current knowledge of the pathogenesis and pathophysiology of diabetes in animal models through a series of reviews in model strains.  The book then continues with vital, established protocols that are employed in the characterization and study of animal models of diabetes.  As a volume in the highly successful Methods in Molecular Biology™ series, this work contains the type of detailed description and key implementation advice necessary to achieve successful results.

 

Authoritative and cutting-edge, Animal Models in Diabetes Research delivers essential content that will be an important resource to advance diabetes research in the years to come.

Keywords

Animal models Diabetes mellitus Experimental diabetology Pathogenesis Pathophysiology Type 1 and type 2 diabetes

Editors and affiliations

  • Hans-Georg Joost
    • 1
  • Hadi Al-Hasani
    • 2
  • Annette Schürmann
    • 3
  1. 1., Department of PharmacologyGerman Institute of Human NutritionNuthetalGermany
  2. 2.German Diabetes Centre, Clinical Biochemistry &PathobiochemistryHeinrich Heine University DüsseldorfDüsseldorfGermany
  3. 3., Department of Experimental DiabetologyGerman Institute of Human NutritionNuthetalGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-62703-068-7
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-067-0
  • Online ISBN 978-1-62703-068-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book