The Centrosome

Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease

  • Heide Schatten

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Centrosomes in Reproduction

  3. Cell and Molecular Biology of Centrosomes

  4. Centrosome Abnormalities in Cancer

    1. Front Matter
      Pages 199-199
    2. Chiara Saladino, Emer Bourke, Ciaran G. Morrison
      Pages 223-241
    3. Zeina Kais, Jeffrey D. Parvin
      Pages 243-253
    4. Benedict Yan, Wee-Joo Chng
      Pages 255-276
    5. Alwin Krämer, Simon Anderhub, Bettina Maier
      Pages 285-305
  5. Centrosomes in Other Systems

    1. Front Matter
      Pages 307-307
    2. Leandro Lemgruber, Marek Cyrklaff, Freddy Frischknecht
      Pages 327-346
    3. Jacek Z. Kubiak, Claude Prigent
      Pages 347-363
    4. Martin Poenie, Laura Christian, Sarah Tan, Yuri Sykulev
      Pages 365-383
    5. Jeffrey L. Salisbury
      Pages 385-391
  6. Back Matter
    Pages 393-396

About this book


This book features a diversity of aspects on centrosome biology focused on the role of centrosomes in reproduction, cell and molecular biology of centrosomes, centrosome abnormalities in cancer, and centrosomes in various cell systems. Each section contains a variety of different subtopics written by experts in their respective fields who have contributed significant new knowledge to decipher structure and the multiple functions of this still intriguing central organelle. The chapters include comprehensive and concise reviews of key topics in the field as well as cell and molecular details that are important for the specific subtopics. Cutting edge new information is balanced with background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. In addition, several articles will raise awareness of centrosomes in areas that have not yet considered centrosomes associated with disease including aspects of misguided signal transduction and several others that may find centrosomes as new targets for therapeutic intervention. The topics addressed are selected to be of interest to scientists, students, teachers, and to all who are interested in expanding their knowledge related to centrosomes. The book is intended for a large audience as a reference book on the subject.


Cell mechanisms Centrosome Imaging Molecular Biology Molecular mechanisms

Editors and affiliations

  • Heide Schatten
    • 1
  1. 1.Dept. Veterinary PathobiologyUniversity of Missouri-ColumbiaColumbiaUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press, a part of Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-62703-034-2
  • Online ISBN 978-1-62703-035-9
  • Buy this book on publisher's site