Clinical Applications of Capillary Electrophoresis

Methods and Protocols

  • Terry M. Phillips
  • Heather Kalish

Part of the Methods in Molecular Biology book series (MIMB, volume 919)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Overview

    1. Front Matter
      Pages 1-1
    2. David S. Hage
      Pages 3-10
  3. Applications in Clinical Chemistry

    1. Front Matter
      Pages 11-11
    2. Angelo Zinellu, Salvatore Sotgia, Luca Deiana, Ciriaco Carru
      Pages 35-42
    3. Dieter Vanderschaeghe, Andras Guttman, Nico Callewaert
      Pages 87-96
  4. Applications in Hematology

    1. Front Matter
      Pages 111-111
    2. James Chun-I Lee, Hsing-Mei Hsieh, Hsiao-Feng Teng, Li-Chin Tsai
      Pages 113-120
    3. Frédéric Cotton, Béatrice Gulbis
      Pages 121-130
  5. Applications in Bacteriology and Virology

    1. Front Matter
      Pages 147-147
    2. Bogusław Buszewski, Katarzyna Hrynkiewicz, Ewelina Dziubakiewicz
      Pages 149-154
    3. Julia A. Fruetel, Victoria A. VanderNoot
      Pages 165-177
  6. Applications in Disease Biomarker Discovery

    1. Front Matter
      Pages 179-179
    2. Xueping Fang, Chenchen Wang, Cheng S. Lee
      Pages 181-187
    3. Pamela N. Nge, Jayson V. Pagaduan, Weichun Yang, Adam T. Woolley
      Pages 189-201
    4. Amaya Albalat, Julia Franke, Julien Gonzalez, Harald Mischak, Petra Zürbig
      Pages 203-213
    5. Angel Puerta, Pedro J. Martin-Alvarez, Sara Ongay, Jose C. Diez-Masa, Mercedes de Frutos
      Pages 215-230
  7. Applications in Immunology

    1. Front Matter
      Pages 231-231
    2. Akwasi A. Apori, Amy E. Herr
      Pages 233-248
    3. Dieter Vanderschaeghe, Evi Debruyne, Hans Van Vlierberghe, Nico Callewaert, Joris Delanghe
      Pages 249-257
    4. Mark Mendonca, Heather Kalish
      Pages 259-271
  8. Applications in Clinical Genetic Analysis

    1. Front Matter
      Pages 273-273
    2. Rong Mao, Pinar Bayrak-Toydemir, Elaine Lyon
      Pages 275-285
    3. Natalia Elfimova, Wafa Amer, Margarete Odenthal
      Pages 287-296
  9. Back Matter
    Pages 309-311

About this book


Capillary electrophoresis (CE) is a powerful and rapid tool for performing complex analyses of a number of different molecular species ranging from small inorganic ions to large nucleic acid fragments and proteins. It is quickly becoming established as a useful tool in clinical medicine due to its consumption of minute samples (less than a microlitre), low reagent costs, and extreme sensitivity, depending upon the source of detection used.  Clinical Applications of Capillary Electrophoresis aims to give an in-depth manual of CE applications in several important areas of clinical science.  Divided into seven sections, this volume provides a brief overview of how CE has been applied in clinical settings, followed by several chapters on CE analysis of important diagnostic molecules and biofluids, as well as descriptions of applications in clinical chemistry, hematology, bacteriology, virology, disease-associated biomarker discovery, immunology and genetic analysis. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Clinical Applications of Capillary Electrophoresis seeks to serve as a valuable source of information not only for clinical pathologists, but also clinical scientists who wish to apply the technique to diagnosis and research.


bacteriology capillary electrophoresis clinical chemistry disease biomarker discovery hematology immunology virology

Editors and affiliations

  • Terry M. Phillips
    • 1
  • Heather Kalish
    • 2
  1. 1.BethesdaUSA
  2. 2.NIBIBNational Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-028-1
  • Online ISBN 978-1-62703-029-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site