Genetically Encoded Functional Indicators

  • Jean-René Martin

Part of the Neuromethods book series (NM, volume 72)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Ludovic Tricoire, Estelle Drobac, Bertrand Lambolez
    Pages 27-42
  3. Antonia Strutz, Thomas Völler, Thomas Riemensperger, André Fiala, Silke Sachse
    Pages 43-70
  4. Soh Kohatsu, Masayuki Koganezawa, Daisuke Yamamoto
    Pages 103-112
  5. Robert A. A. Campbell, Kyle S. Honegger, Eyal Gruntman, Glenn C. Turner
    Pages 113-124
  6. Jasper Akerboom, Lin Tian, Jonathan S. Marvin, Loren L. Looger
    Pages 125-147
  7. Back Matter
    Pages 169-169

About this book


In the last decade, several different optical imaging techniques, either based on various voltage or calcium dyes, or more recently on modified fluorescent or bioluminescent proteins (genetically encoded) that are sensitive to calcium, have been developed to study neuronal activity, and especially groups of neurons, with the goal of mapping and deciphering the neural code underlying major neurophysiological functions.  Genetically Encoded Functional Indicators brings together expert contributors to present the development of recent genetic techniques that allow for generating genetically encoded activity sensors in order to investigate neuronal activity. Each chapter describes a specific sensor and its utilization to study neuronal activity in a particular way.  Written in the Neuromethods series style, chapters contain the kind of key description and implementation advice that guarantees successful results.


Helpful and easy to use, Genetically Encoded Functional Indicators aims to inspire students and researchers and to serve as a useful guide to those who wish to start using these different brain imaging techniques and require a bit of guidance in how best to choose a technique to match the goal of their study.


Brain visualization Calcium imaging Neural circuits Neuroimaging Neuronal activity Neurophysiology

Editors and affiliations

  • Jean-René Martin
    • 1
  1. 1.ICFC, Neurobiologie & DeveloppementCNRS, UPR-3294Gif-sur-YvetteFrance

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-62703-013-7
  • Online ISBN 978-1-62703-014-4
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site