© 2012

Active Surveillance for Localized Prostate Cancer

A New Paradigm for Clinical Management

  • Laurence Klotz

Part of the Current Clinical Urology book series (CCU)

Table of contents

  1. Front Matter
    Pages i-xi
  2. John B. Eifler, H. Ballentine Carter
    Pages 9-21
  3. Michael J. Donovan, Carlos Cordon-Cardo
    Pages 23-34
  4. Danny Vesprini, Robert Nam
    Pages 35-54
  5. S. Y. Jackie Sham, Chris Parker
    Pages 55-65
  6. Caroline M. Moore, Clare Allen, Mark Emberton
    Pages 67-80
  7. Meelan Bul, Monique J. Roobol, Chris H. Bangma
    Pages 81-94
  8. Laurence Klotz
    Pages 95-105
  9. Meredith Wallace Kazer, Dwanna M. Ward-Boahen, David M. Latini, Donald E. Bailey Jr.
    Pages 107-119
  10. Liying Zhang, Laurence Klotz
    Pages 131-137
  11. Lionne D. F. Venderbos, Chris H. Bangma, Ida J. Korfage
    Pages 157-168
  12. Marc A. Dall’Era, Christopher P. Evans
    Pages 179-185
  13. Sima P. Porten, Jared M. Whitson, Peter R. Carroll
    Pages 187-199
  14. Back Matter
    Pages 201-208

About this book


Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management.  The book will also be of interest to scientifically literate patients and their families.   The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehensive guide to the management of patients on surveillance. The volume covers the many complexities and nuances to this approach including, patient selection, risk assessment, how to overcome 'cancer hysteria' when counseling patients, identifying appropriate triggers for intervention, use of PSA kinetics and MR imaging information, technique and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.


GLMM technique GLMM technique MRI and surveillance MRI and surveillance PSA kinetics PSA kinetics Risk stratification Risk stratification

Editors and affiliations

  • Laurence Klotz
    • 1
  1. 1.University of Toronto, Sunnybrook Health Sciences CentreDivision of UrologyTorontoCanada

Bibliographic information

  • Book Title Active Surveillance for Localized Prostate Cancer
  • Book Subtitle A New Paradigm for Clinical Management
  • Editors Laurence Klotz
  • Series Title Current Clinical Urology
  • DOI
  • Copyright Information Springer Science+Business Media New York 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-61779-911-2
  • eBook ISBN 978-1-61779-912-9
  • Edition Number 1
  • Number of Pages XI, 208
  • Number of Illustrations 11 b/w illustrations, 22 illustrations in colour
  • Topics Urology
    Imaging / Radiology
  • Buy this book on publisher's site


From the reviews:

“The concept of active surveillance (AS) was developed by Klotz, with the aim of limiting the risk of overtreatment in patients with low-risk cancers, while providing timely radical treatment for those requiring it. Currently, this concept is supported by an increasing number of urologists. … This excellent overview dedicated to AS fills a lack in the literature. … this textbook can be recommended to all physicians involved in prostate cancer management.” (European Urology Today, Vol. 25 (2), March-May, 2013)

“This book summarizes the current worldwide experience with active surveillance for prostate cancer. … this book is appropriate for primary care physicians, surgeons, medical oncologists, radiation oncologists, pathologists, radiologists, psychiatrists, and psychologists. Furthermore, it would be valuable to the general audience and patients as it clearly describes the role and implications of active surveillance in the treatment of prostate cancer. … I strongly recommend this book to any clinician whose practice involves the treatment of patients with prostate cancer in any capacity.” (Sanjay Kasturi, Doody’s Book Reviews, October, 2012)