Methods and Protocols

  • Cristina Costa
  • Rafael Máñez

Part of the Methods in Molecular Biology book series (MIMB, volume 885)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Veronica Tisato, Emanuele Cozzi
    Pages 1-16
  3. Mireia Uribe-Herranz, Cristina Costa
    Pages 17-31
  4. Mireia Uribe-Herranz, Cristina Costa
    Pages 33-45
  5. Dale Christiansen, Effie Mouhtouris, Paul A. Ramsland, Mauro S. Sandrin
    Pages 47-56
  6. Cristiana Bulato, Claudia Radu, Paolo Simioni
    Pages 71-89
  7. Roberta Sommaggio, Magdiel Pérez-Cruz, Cristina Costa
    Pages 91-103
  8. Angelica M. Giraldo, Suyapa Ball, Kenneth R. Bondioli
    Pages 105-123
  9. Johannes Postrach, Andreas Bauer, Michael Schmoeckel, Bruno Reichart, Paolo Brenner
    Pages 155-168
  10. Lars Burdorf, Agnes M. Azimzadeh, Richard N. Pierson III
    Pages 169-189
  11. Karin Ulrichs, Sibylle Eber, Bianca Schneiker, Sabine Gahn, Armin Strauß, Vasiliy Moskalenko et al.
    Pages 213-232
  12. Xavier Lévêque, Véronique Nerrière-Daguin, Isabelle Neveu, Philippe Naveilhan
    Pages 233-243
  13. Katia R. F. Lima-Quaresma, Andre Gustavo Bonavita, Matheus Kafuri Cytrangulo, Marcelo Alves Pinto, Luiz Anastácio Alves
    Pages 245-249
  14. Prado SM Díaz, Fuentes-Boquete IM, Blanco FJ
    Pages 251-261
  15. Giada Mattiuzzo, Yasuhiro Takeuchi, Linda Scobie
    Pages 263-279
  16. María Jorqui Azofra, Carlos María Romeo Casabona
    Pages 307-329
  17. Prado SM Díaz, Fuentes-Boquete IM, Blanco FJ
    Pages E1-E1
  18. Back Matter
    Pages 331-335

About this book


Despite many technological challenges faced by the xenotransplantation field, many major advances have been made in the last two decades. The field seeks to overcome the limitations and difficulties in organ procurement, which also apply to human cells and tissues, and facilitate the development of new therapies based on cell and engineered-tissue. Xenogeneic cells are simpler than solid organs and seem to pose less hurdles to attain long-term graft survival. In, Xenotransplantation: Methods and Protocols expert researchers study characterizations of xenogeneic interactions at the cellular and molecular levels and describe the use of relevant small-animal and pig-to-primate models. Related ethical and legal considerations are also covered. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.


Thorough and intuitive, Xenotransplantation: Methods and Protocols aids scientists in continuing to study xenotransplantation and its multiple aspects.


Xenogeneic cells allogeneic organs allotransplantion carbohydrates immune responses proteins regenerative medicine xenograft rejection xenotransplantation

Editors and affiliations

  • Cristina Costa
    • 1
  • Rafael Máñez
    • 2
  1. 1.Bellvitge (IDIBELL), Hospital Duran i ReynalsInstitut d'Investigació Biomèdica deL’Hospitalet de LlobregatSpain
  2. 2.Servicio de Medicina IntensivaHospital Universitario de BellvitgeL'Hospitalet de LlobregatSpain

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-844-3
  • Online ISBN 978-1-61779-845-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site