Psychiatric Disorders

Methods and Protocols

  • Firas H. Kobeissy

Part of the Methods in Molecular Biology book series (MIMB, volume 829)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Overview of the Animal Research in Psychiatric Illness and Substance Abuse

    1. Front Matter
      Pages 1-1
    2. Arie Kaffman, John J. Krystal
      Pages 3-30
    3. Mahdi Razafsha, Hura Behforuzi, Hassan Azari, Zhiqun Zhang, Kevin K. Wang, Firas H. Kobeissy et al.
      Pages 49-62
  3. Methods in Animal Models of Psychiatric Illness

    1. Front Matter
      Pages 63-63
    2. Alicia Izquierdo, Annabelle M. Belcher
      Pages 85-101
    3. Ying Xu, Philip A. Barish, Jianchun Pan, William O. Ogle, James M. O’Donnell
      Pages 103-124
    4. David H. Overstreet
      Pages 125-144
    5. Michael Guidi, Thomas C. Foster
      Pages 145-153
    6. Darragh P. Devine
      Pages 155-163
    7. Nicholas W. Simon, Barry Setlow
      Pages 165-175
    8. Mahendra Bishnoi, Ravneet K. Boparai
      Pages 193-201
  4. Methods in Animal Models of Substance Abuse

    1. Front Matter
      Pages 203-203
    2. Darin J. Knapp, George R. Breese
      Pages 205-230
    3. Jennifer A. DiNieri, Yasmin L. Hurd
      Pages 231-242
    4. Stephanie Caille, Kelly Clemens, Luis Stinus, Martine Cador
      Pages 243-256
    5. Firas H. Kobeissy, Jeremiah D. Mitzelfelt, Irina Fishman, Drake Morgan, Roger Gaskins, Zhiqun Zhang et al.
      Pages 269-278
    6. Benjamin A. Zimmer, David C. S. Roberts
      Pages 279-290
    7. Carson V. Dobrin, David C. S. Roberts
      Pages 291-302
    8. Erik B. Oleson, David C. S. Roberts
      Pages 303-319
    9. Drake Morgan, Jameson P. DuPree, Alex D. Bibbey, Glen M. Sizemore
      Pages 321-327
    10. Joy Guingab-Cagmat, Rayna M. Bauzo, Adrie W. Bruijnzeel, Kevin K. Wang, Mark S. Gold, Firas H. Kobeissy
      Pages 329-348
  5. Methods in Animal Models of Eating Disorders

    1. Front Matter
      Pages 349-349
    2. Nicole M. Avena, Miriam E. Bocarsly, Bartley G. Hoebel
      Pages 351-365
    3. Neil E. Rowland
      Pages 367-375
    4. Stephanie J. Klenotich, Stephanie C. Dulawa
      Pages 377-393
  6. Biomarkers, Neuroendocrine and Inflammatory Profiles Relevant to Neuropsychiatric Disorders

  7. “Omics” Analysis and Systems Biology Applications in Psychiatric Disorders

    1. Front Matter
      Pages 469-469
    2. Antoniette M. Maldonado-Devincci, Stanley M. Stevens Jr., Cheryl L. Kirstein
      Pages 471-485
    3. Julia S. Gelman, Jonathan Wardman, Vadiraja B. Bhat, Fabio C. Gozzo, Lloyd D. Fricker
      Pages 487-503
    4. Yoshinori Masuo, Junko Shibato, Randeep Rakwal
      Pages 505-530
    5. Michaela D. Filiou, Christoph W. Turck
      Pages 531-539
    6. Pietro Paolo Sanna, Vez Repunte-Canonigo, Alessandro Guidotti
      Pages 541-550
    7. Diego Tovar, Eduardo Cornejo, Petros Xanthopoulos, Mario R. Guarracino, Panos M. Pardalos
      Pages 593-603
  8. Arie Kaffman, John J. Krystal
    Pages E1-E1
  9. Back Matter
    Pages 605-610

About this book


New high throughput techniques in neuroscience and psychiatry have enhanced the development of experimental, customizable animal models that are predictive of human neuropsychiatric pathology and give vital insights on the mechanisms and pathways involved. In Psychiatric Disorders: Methods and Protocols, key experts have written integrated chapters on neuropsychiatric research sharing their insightful expertise and opinions focusing on both the animal models as well as the cutting edge techniques applied. Beginning with an overview of the animal research in psychiatric illness and substance abuse, this comprehensive volume continues with the modeling of neuropsychiatric illness, drug abuse paradigms and techniques, biomarker identification, autoimmune inflammatory response, and neuroendocrine alteration in the areas of psychiatry, as well as state-of-the-art “Omics approaches” and neurosystems biology/data mining techniques to compute and analyze genomic and proteomics alteration occurring within neuropsychiatric models.  As a part of the highly successful Methods in Molecular Biology™ series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Thorough and easily applicable, Psychiatric Disorders: Methods and Protocols offers the detailed and clearly illustrated tools necessary for neuroscientists and psychiatrists to handle many unanswered scientific questions with a more creative and insightful approach.


Animal models Drug abuse Mental illness Neuropsychiatric research Omics approaches Psychiatric disorders Substance abuse

Editors and affiliations

  • Firas H. Kobeissy
    • 1
  1. 1.McKnight Brain Institute, Department of PsychiatryUniversity of FloridaGainesvilleUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-457-5
  • Online ISBN 978-1-61779-458-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site