Genetic Toxicology

Principles and Methods

  • James M. Parry
  • Elizabeth M. Parry

Part of the Methods in Molecular Biology book series (MIMB, volume 817)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. David Gatehouse
    Pages 21-34
  3. Melvyn Lloyd, Darren Kidd
    Pages 35-54
  4. Ann T. Doherty
    Pages 121-141
  5. Brian Burlinson
    Pages 143-163
  6. Karen Brown
    Pages 207-230
  7. Richard M. Walmsley, Matthew Tate
    Pages 231-250
  8. Ann T. Doherty, Adi Baumgartner, Diana Anderson
    Pages 271-304
  9. Raluca A. Mateuca, Ilse Decordier, Micheline Kirsch-Volders
    Pages 305-334
  10. Ilse-Dore Adler, Francesca Pacchierotti, Antonella Russo
    Pages 335-375
  11. Ian de G. Mitchell, David O. F. Skibinski
    Pages 399-417
  12. Back Matter
    Pages 419-433

About this book


The evaluation of potential mutagenic activity is a critical step in the assessment of the safety of both new and pre-existing chemical types. In Genetic Toxicology: Principles and Methods, expert contributors help to satisfy the demand for education in this tremendously important area of study.  The volume covers three basic areas: the scientific basis of the discipline, the methodologies of the main test assays, and the application of the methods, all aimed primarily at scientists in the safety departments of the industries working with both natural and synthetic chemicals.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Intuitive and cutting-edge, Genetic Toxicology: Principles and Methods provides crucial support to both laboratory workers in providing quality information on the appropriate application of techniques and to study directors in their assay selection and protocol design in this vital field.


Cytogenetic methods Genetic toxicology Mutagenicity testing Natural and synthetic chemicals Transgenic animals

Editors and affiliations

  • James M. Parry
    • 1
  • Elizabeth M. Parry
    • 2
  1. 1.LyndhurstUnited Kingdom
  2. 2.LyndhurstUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-420-9
  • Online ISBN 978-1-61779-421-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site