© 2012

Gestational Trophoblastic Disease

Diagnostic and Molecular Genetic Pathology

  • Pei Hui

Part of the Current Clinical Pathology book series (CCPATH)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Pei Hui
    Pages 57-75
  3. Natalia Buza
    Pages 77-90
  4. Pei Hui
    Pages 91-103
  5. Katja Gwin
    Pages 105-125
  6. Pei Hui
    Pages 127-137
  7. Pei Hui
    Pages 139-145
  8. Pei Hui
    Pages 147-159
  9. Christine E. Richter, Peter E. Schwartz
    Pages 179-194
  10. Back Matter
    Pages 195-205

About this book


In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations.

Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.


Placental site trophoblastic tumor

Editors and affiliations

  • Pei Hui
    • 1
  1. 1., Department of PathologyYale University School of MedicineNew HavenUSA

Bibliographic information

  • Book Title Gestational Trophoblastic Disease
  • Book Subtitle Diagnostic and Molecular Genetic Pathology
  • Editors Pei Hui
  • Series Title Current Clinical Pathology
  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-61779-393-6
  • Softcover ISBN 978-1-4939-5924-2
  • eBook ISBN 978-1-61779-394-3
  • Edition Number 1
  • Number of Pages XIII, 205
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pathology
  • Buy this book on publisher's site


From the reviews:

“The book has 12 chapters, each documented by approximately 100 references. … As many of the basic facts are repeated in most chapters, the book is best as a reference book. … Pei Hui has, with great effort, collected and updated knowledge within the field of trophoblastic disease. Overall, the book is well written, covering all aspects and presenting many well-made illustrations. The book serves as a useful handbook, mainly for pathologists with a special interest in trophoblastic disease.” (Isa Niemann, Acta Obstetricia et Gynecologica Scandinavica, Vol. 91 (9), September, 2012)