Animal Models of Movement Disorders

Volume II

  • Emma L. Lane
  • Stephen B. Dunnett
Part of the Neuromethods book series (NM, volume 62)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Basal Ganglia

    1. Front Matter
      Pages 1-1
    2. Miriam A. Hickey, Marie-Françoise Chesselet
      Pages 3-19
    3. Máté D. Döbrössy, Fabian Büchele, Guido Nikkhah
      Pages 21-35
    4. Daniela Kuzdas, Gregor K. Wenning
      Pages 37-54
    5. Mark A. Rossi, Henry H. Yin
      Pages 55-69
    6. Cesar V. Borlongan, Paul R. Sanberg
      Pages 71-89
    7. Tracy D. Farr, Rebecca C. Trueman
      Pages 91-114
  3. Neo- and Allo-Cortical Systems

    1. Front Matter
      Pages 115-115
    2. G. Campbell Teskey, Bryan Kolb
      Pages 117-137
    3. Kevin D. Alloway, Jared B. Smith
      Pages 139-159
    4. Toshihiko Kuroiwa, Richard F. Keep
      Pages 183-191
    5. Frances Corrigan, Jenna M. Ziebell, Robert Vink
      Pages 193-209
  4. Cerebellar and Brain Stem Systems

    1. Front Matter
      Pages 239-239
    2. Robert Lalonde, Catherine Strazielle
      Pages 241-262
    3. Rachel M. Sherrard
      Pages 263-279
    4. Richard F. Thompson
      Pages 281-286
    5. Ma’ayan Semo, Carlos Gias, Anthony Vugler, Peter John Coffey
      Pages 287-320

About this book

Introduction

Movement is the way that animals interact with their environment and is under the organization and complex control of the brain and spinal cord. Multiple central nervous systems, including cortex, basal ganglia, cerebellum, and brainstem, interact to provide precise motor control and integration. Damage or disease within these systems cause profound motor disturbances in man, which can be effectively modeled in animals to develop a better understanding and treatment of the human condition. Animal Models of Movement Disorders introduces a variety of methods and techniques used to model and assess motor function in experimental animals from lower orders, such as drosophila and c. elegans, through vertebrate species including fish, to mammals, such as rodents and non-human primates. The most advanced contemporary models in each system are presented at multiple levels of analysis from molecular and genetic modeling, lesions, anatomy, neurochemistry, to imaging and behavior. Volume II of this detailed collection contains sections on the basal ganglia, neo- and allo-cortical systems, cerebellar and brain stem systems, as well as spinal cord systems.

 

Comprehensive and meticulous, Animal Models of Movement Disorders serves as a valuable reference for those studying motor disorders by covering methodologies in detail and providing the information necessary to consider both the appropriate models and assessment tools that can most informatively answer the key experimental issues in the field.

Keywords

Allo-cortical systems Basal ganglia Brain stem Central nervous system Cerebellar systems Motor dysfunction Neo-cortical systems Spinal cord

Editors and affiliations

  • Emma L. Lane
    • 1
  • Stephen B. Dunnett
    • 2
  1. 1., Welsh School of PharmacologyCardiff UniversityCardiffUnited Kingdom
  2. 2.School of Biosciences, Brain Repair GroupCardiff UniversityCardiffUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-61779-301-1
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-300-4
  • Online ISBN 978-1-61779-301-1
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • About this book