In vivo NMR Imaging

Methods and Protocols

  • Leif Schröder
  • Cornelius Faber

Part of the Methods in Molecular Biology book series (MIMB, volume 771)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Basics of MRI

    1. Front Matter
      Pages 1-1
    2. Rolf Pohmann
      Pages 3-21
    3. Leif Schröder, Cornelius Faber
      Pages 45-67
    4. Volker C. Behr
      Pages 69-88
    5. Patrick McConville
      Pages 89-113
  3. Special Techniques

    1. Front Matter
      Pages 115-115
    2. Frank Kober, Guillaume Duhamel, Virginie Callot
      Pages 117-138
    3. Bernadette Erokwu, Chris Flask, Vikas Gulani
      Pages 139-152
    4. Joan M. Greve
      Pages 153-169
    5. Xiaolei Song, Kannie W.Y. Chan, Michael T. McMahon
      Pages 171-187
    6. Jan Henrik Ardenkjaer-Larsen, Haukur Jóhannesson, J. Stefan Petersson, Jan Wolber
      Pages 205-226
    7. Jeff F. Dunn
      Pages 227-240
    8. Rosa Tamara Branca
      Pages 241-252
  4. Brain Applications

    1. Front Matter
      Pages 253-253
    2. Therése Kallur, Mathias Hoehn
      Pages 255-275
    3. Alize Scheenstra, Jouke Dijkstra, Louise van der Weerd
      Pages 277-291
    4. Alexandra Petiet, Benoit Delatour, Marc Dhenain
      Pages 293-308

About this book

Introduction

Nuclear magnetic resonance imaging represents a technique that is indispensable in every day biomedical diagnostics. Thanks to the numerous ways to manipulate and detect an NMR signal, it is possible to obtain a variety of information with excellent spatial and temporal resolution. Today’s MRI techniques go far beyond the illustration of pure anatomical structures and include the revealing of processes down to the molecular level. The number of small animal imaging centers relying on MRI as a key method for preclinical research to understand diseases and to test for novel treatments is growing rapidly. In Vivo NMR Imaging: Methods and Protocols is written as an experimental laboratory text to provide a descriptive approach of the various applications of magnetic resonance imaging and its underlying principles. Starting from a compact introduction of basic NMR physics and image encoding techniques suitable for a broad audience in the life sciences, the concept focuses on addressing the many ways of generating contrast in MR images. The authors cover an interdisciplinary range of problems to be addressed by this non-invasive modality, including study protocols for addressing morphological, physiological, functional, and biochemical aspects of various tissues in living organisms. Information about practical aspects of designing experimental studies that follow the special conditions for micro imaging setups are also provided.

 

Written in the successful Methods in Molecular Biology™ series format, In Vivo NMR Imaging: Methods and Protocols aims to be an experimental compendium of modern in vivo MR imaging with special focus on recent developments in molecular imaging and new protocols for imaging metabolism and molecular markers.

Keywords

In vivo MRI intermolecular multiple-quantum coherences metabolic imaging murine vasculature nuclear magnetic resonance phenotyping spatial encoding spectroscopic imaging spin echo targeted imaging

Editors and affiliations

  • Leif Schröder
    • 1
  • Cornelius Faber
    • 2
  1. 1.ERC Project BiosensorImagingLeibniz-Institut für Molekulare PharmakoBerlinGermany
  2. 2.Inst. Klinische Radiologie, AG ExperimentelleUniversität MünsterMünsterGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-61779-219-9
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-218-2
  • Online ISBN 978-1-61779-219-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book