Yeast Genetic Networks

Methods and Protocols

  • Attila Becskei

Part of the Methods in Molecular Biology book series (MIMB, volume 734)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Experimental Analysis of Signalling in Gene Regulatory Networks

    1. Front Matter
      Pages 1-1
    2. Julia Marín-Navarro, Alexandra Jauhiainen, Joaquín Moreno, Paula Alepuz, José E. Pérez-Ortín, Per Sunnerhagen
      Pages 3-23
    3. José García-Martínez, Vicent Pelechano, José E. Pérez-Ortín
      Pages 25-44
    4. Prasuna Ratna, Attila Becskei
      Pages 45-61
    5. Dmitry Nevozhay, Rhys M. Adams, Gábor Balázsi
      Pages 81-100
  3. Mathematical Modelling of Network Behavior

    1. Front Matter
      Pages 121-121
    2. Xiu-Deng Zheng, Yi Tao
      Pages 123-151
    3. Tormod Drengstig, Thomas Kjosmoen, Peter Ruoff
      Pages 153-172
    4. Jacqueline Garcia, Kellie J. Sims, John H. Schwacke, Maurizio Del Poeta
      Pages 173-200
  4. Analysis of Network Behaviour by Quantitative Genetics

    1. Front Matter
      Pages 221-221
    2. Steffen Fehrmann, Gaël Yvert
      Pages 223-240
    3. Arthur Berg, Ning Li, Chunfa Tong, Zhong Wang, Scott A. Berceli, Rongling Wu
      Pages 241-255
  5. Examination of Network Behaviour in Related Yeast Species

    1. Front Matter
      Pages 257-257
    2. Alejandro Juárez-Reyes, Alejandro De Las Peñas, Irene Castaño
      Pages 279-301
    3. Arpita Singh, Asfia Qureshi, Maurizio Del Poeta
      Pages 317-333
  6. Back Matter
    Pages 335-344

About this book


Regulation of gene expression, a major determinant of gene activity, occupies a central place in molecular biology. Yeast Genetic Networks: Methods and Protocols covers approaches to the systems biological analysis of small-scale gene networks in yeast. Divided into four convenient sections, this detailed volume discusses the methods used to analyze gene expression quantitatively, presents a collection of mathematical and computational tools to analyze stochasticity, adaptation, sensitivity in signal transmission, and oscillations in gene expression, provides instructional methods on how to utilize the tools of quantitative genetics to identify genes that regulate stochasticity and oscillations in gene expression, and concludes with a section devoted to the analysis of conserved gene expression systems and networks in different fungal species. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.


Authoritative and accessible, Yeast Genetic Networks: Methods and Protocols serves as an ideal and valuable resource for both novices and experienced researchers.


Fungal pathogenicity Gene regulatory networks Gene signalling Mathematical modelling Network behavior Quantitative genetics Synthetic Networks

Editors and affiliations

  • Attila Becskei
    • 1
  1. 1.Biochemisches InstitutUniversität ZürichZürichSwitzerland

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-085-0
  • Online ISBN 978-1-61779-086-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site