Regenerating the Heart

Stem Cells and the Cardiovascular System

  • Ira S. Cohen
  • Glenn R. Gaudette

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Ira S. Cohen, Glenn R. Gaudette
    Pages 1-3
  3. Stem Cells for Regeneration of Mechanical Function

    1. Front Matter
      Pages 5-5
    2. Alexander M. Becker, Michael Rubart, Loren J. Field
      Pages 7-24
    3. Isotta Chimenti, Roberto Gaetani, Lucio Barile, Elvira Forte, Vittoria Ionta, Francesco Angelini et al.
      Pages 131-147
    4. Antonio Paolo Beltrami, Daniela Cesselli, Carlo Alberto Beltrami
      Pages 149-171
    5. Zipora Yablonka-Reuveni, Kenneth Day
      Pages 173-200
    6. Todd K. Rosengart, Bishawi B. S. Muath
      Pages 201-217
    7. Raymond L. Page, Christopher Malcuit, Tanja Dominko
      Pages 219-239
    8. Naama Zeevi-Levin, Joseph Itskovitz-Eldor
      Pages 241-261
    9. Timothy J. Nelson, Andre Terzic
      Pages 263-280
  4. Stem Cells for Regeneration of Electrical Function

  5. Regenerating Cardiac Tissues

    1. Front Matter
      Pages 391-391
    2. Tracy A. Gwyther, Marsha W. Rolle
      Pages 393-402
    3. Benedikt Weber, Simon P. Hoerstrup
      Pages 403-442
    4. Amandine F. G. Godier-Furnémont, Yi Duan, Robert Maidhof, Gordana Vunjak-Novakovic
      Pages 443-475
  6. Technical Issues for Stem Cell Therapy in the Heart

    1. Front Matter
      Pages 477-477
    2. Sarah Fernandes, Hans Reinecke
      Pages 479-498
    3. Yingli Fu, Dara L. Kraitchman
      Pages 499-521
    4. Jacques P. Guyette, Glenn R. Gaudette
      Pages 523-542
  7. Back Matter
    Pages 543-556

About this book


Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield.

Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium.

This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.


Biotechnology Cardio Regenerative Medicine Stem Cell

Editors and affiliations

  • Ira S. Cohen
    • 1
  • Glenn R. Gaudette
    • 2
  1. 1.Health Sciences Center, Dept. Physiology & BiophysicsStony Brook UniversityStony BrookUSA
  2. 2.Worcester Polytechnic InstituteWorcesterUSA

Bibliographic information