Male Germline Stem Cells: Developmental and Regenerative Potential

  • Kyle E. Orwig
  • Brian P. Hermann

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Germline Developmental Potential

    1. Front Matter
      Pages 1-1
    2. Sonya M. Schuh-Huerta, Renee A. Reijo Pera
      Pages 49-86
  3. Spermatogonial Stem Cells

  4. Translation and Regenerative Potential of Spermatogonial Stem Cells

    1. Front Matter
      Pages 177-177
    2. Gunapala Shetty, Gensheng Wang, Marvin L. Meistrich
      Pages 179-203
    3. Stefan Schlatt, Jose R. Rodriguez-Sosa, Ina Dobrinski
      Pages 205-225
    4. Brian P. Hermann, Kyle E. Orwig
      Pages 227-253
  5. Back Matter
    Pages 255-262

About this book


Scientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers in the field, Male Germline Stem Cells: Developmental and Regenerative Potential assesses the implications of these discoveries for understanding the fundamental biology of germline stem cells as well as their potential for human stem cell-based therapies. This monograph covers many of the fundamental issues now being explored by today’s generation of stem cell researchers, including the field’s potential for regenerative medicine. Ranging from an assessment of the pluripotency of primordial germ cells and their possible applications in treating testicular cancer, to the recovery of once-mordant fertilization-competent sperm, this volume has it all. It is a reference point for any scientist involved in related research as well as being a timely summation of what could prove to be a hugely exciting and very fruitful area of inquiry.


genome threads germline stem cell

Editors and affiliations

  • Kyle E. Orwig
    • 1
  • Brian P. Hermann
    • 2
  1. 1.Magee-Womens Research InstituteUniversity of PittsburghPittsburghUSA
  2. 2.Magee-Womens Research InstituteUniversity of PittsburghPittsburghUSA

Bibliographic information