Experimental and Applied Immunotherapy

  • Jeffrey Medin
  • Daniel Fowler

Table of contents

  1. Front Matter
    Pages i-xvii
  2. T Cell Therapy: State-of-the-Art

    1. Front Matter
      Pages 1-1
  3. Non-T Cell Therapeutic Approaches

    1. Front Matter
      Pages 35-35
    2. David Spaner, Angela Bahlo
      Pages 37-57
    3. Christoph Rader
      Pages 59-83
    4. Yoko Kosaka, Armand Keating
      Pages 85-105
    5. Elizabeth Scheid, Michael Ricci, Ronan Foley
      Pages 107-126
    6. Moïra François, Jacques Galipeau
      Pages 127-148
  4. T Cell Therapeutic Approaches

    1. Front Matter
      Pages 149-149
    2. Brad H. Nelson, John R. Webb
      Pages 151-172
    3. Jacques Thibodeau, Marie-Claude Bourgeois-Daigneault, Réjean Lapointe
      Pages 173-194
    4. Adele Y. Wang, Megan K. Levings
      Pages 207-228
    5. Wolfgang Zimmermann, Robert Kammerer
      Pages 229-249
  5. Non-Cellular Aspects of Cancer Immunotherapy

    1. Front Matter
      Pages 279-279
    2. Megan Nelles, Vincenzo Salerno, Yixin Xu, Christopher J. Paige
      Pages 281-305
    3. Natalie Grinshtein, Jonathan Bramson
      Pages 323-338

About this book

Introduction

Immunotherapy is now recognized as an essential component of treatment for a wide variety of cancers. It is an interdisciplinary field that is critically dependent upon an improved understanding of a vast network of cross-regulatory cellular populations and a diversity of molecular effectors; it is a leading example of translational medicine with a favorable concept-to-clinical-trial timeframe of just a few years. There are many established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic and more cost effective than many therapies currently in use. Experimental and Applied Immunotherapy is a state-of-the-art text offering a roadmap leading to the creation of these future cancer-fighting immunotherapies. It includes essays by leading researchers that cover a wide variety of topics including T cell and non-T cell therapy, monoclonal antibody therapy, dendritic cell-based cancer vaccines, mesenchymal stromal cells, negative regulators in cancer immunology and immunotherapy, non-cellular aspects of cancer immunotherapy, the combining of cancer vaccines with conventional therapies, the combining of oncolytic viruses with cancer immunotherapy, transplantation, and more. The field of immunotherapy holds great promise that will soon come to fruition if creative investigators can bridge seemingly disparate disciplines, such as T cell therapy, gene therapy, and transplantation therapy. This text is a vital tool in the building of that bridge.

Keywords

Cancer Immunotherapy translational immunotherapy

Editors and affiliations

  • Jeffrey Medin
    • 1
  • Daniel Fowler
    • 2
  1. 1.University Health NetworkUniversity of TorontoTorontoCanada
  2. 2.National Cancer Institute, Experimental Transplatation &National Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-980-2
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-60761-979-6
  • Online ISBN 978-1-60761-980-2
  • About this book