Tumor Models in Cancer Research

  • Beverly A.┬áTeicher
Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Shannon Decker, Edward Sausville
      Pages 3-20
  3. Transplantable Syngeneic Rodent Tumors

    1. Front Matter
      Pages 21-21
    2. William R. Waud
      Pages 23-41
    3. Lisa Polin, Thomas H. Corbett, Bill J. Roberts, Alfred J. Lawson, Wilbur R. Leopold III, Kathryn White et al.
      Pages 43-78
  4. Human Tumor Xenografts

    1. Front Matter
      Pages 97-97
    2. Ming Liu, Daniel Hicklin
      Pages 99-124
    3. Heinz-Herbert Fiebig, Angelika M. Burger
      Pages 167-193
    4. Christopher L. Morton, Peter J. Houghton
      Pages 195-213
    5. Vinod Kaimal, Wilbur R. Leopold, Patrick McConville
      Pages 215-241
  5. Carcinogen-Induced Tumors

    1. Front Matter
      Pages 243-243
    2. Henry J. Thompson
      Pages 245-255
  6. Disease and Target-Specific Models

    1. Front Matter
      Pages 257-257
    2. Ene T. Fairchild, William E. Carson III
      Pages 259-285
    3. Harvey I. Pass, Joseph B. Pincus, Michele Carbone, Magdalena Plasilova
      Pages 307-324

About this book

Introduction

Beverly A. Teicher and a panel of leading experts comprehensively describe the state-of-the-art in animal tumor model research. This volume updates and extends the comprehensive presentations in the first edition. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, and genetically engineered mouse models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research 2nd edition, provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.

Keywords

Cancer Research Metastastic Syngeneic Teicher Tumor Models Xenograft

Editors and affiliations

  • Beverly A.┬áTeicher
    • 1
  1. 1.Genzyme CorporationBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-968-0
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine
  • Print ISBN 978-1-60761-967-3
  • Online ISBN 978-1-60761-968-0
  • About this book