Tumor Models in Cancer Research

  • Beverly A.┬áTeicher

Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Shannon Decker, Edward Sausville
      Pages 3-20
  3. Transplantable Syngeneic Rodent Tumors

    1. Front Matter
      Pages 21-21
    2. William R. Waud
      Pages 23-41
    3. Lisa Polin, Thomas H. Corbett, Bill J. Roberts, Alfred J. Lawson, Wilbur R. Leopold III, Kathryn White et al.
      Pages 43-78
  4. Human Tumor Xenografts

    1. Front Matter
      Pages 97-97
    2. Ming Liu, Daniel Hicklin
      Pages 99-124
    3. Heinz-Herbert Fiebig, Angelika M. Burger
      Pages 167-193
    4. Christopher L. Morton, Peter J. Houghton
      Pages 195-213
    5. Vinod Kaimal, Wilbur R. Leopold, Patrick McConville
      Pages 215-241
  5. Carcinogen-Induced Tumors

    1. Front Matter
      Pages 243-243
    2. Henry J. Thompson
      Pages 245-255
  6. Disease and Target-Specific Models

    1. Front Matter
      Pages 257-257
    2. Ene T. Fairchild, William E. Carson III
      Pages 259-285
    3. Harvey I. Pass, Joseph B. Pincus, Michele Carbone, Magdalena Plasilova
      Pages 307-324
    4. David M. Vail, Douglas H. Thamm
      Pages 353-373
  7. Genetically Engineered Mouse Models of Cancer

  8. Metastasis Models

    1. Front Matter
      Pages 445-445
  9. Normal Tissue Response Models

    1. Front Matter
      Pages 497-497
    2. Stephen T. Sonis, Gregory Lyng, Kimberly Pouliot
      Pages 499-519
    3. Thies Schroeder, Siqing Shan, Mark W. Dewhirst
      Pages 553-568
  10. Experimental Methods and Endpoints

    1. Front Matter
      Pages 569-569
    2. Beverly A. Teicher
      Pages 571-605
    3. Sara Rockwell
      Pages 607-624
    4. L. C. Stephens, L. Milas, K. K. Ang, K. A. Mason, R. E. Meyn
      Pages 625-640
  11. Back Matter
    Pages 681-693

About this book


Beverly A. Teicher and a panel of leading experts comprehensively describe the state-of-the-art in animal tumor model research. This volume updates and extends the comprehensive presentations in the first edition. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, and genetically engineered mouse models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research 2nd edition, provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.


Cancer Research Metastastic Syngeneic Teicher Tumor Models Xenograft

Editors and affiliations

  • Beverly A.┬áTeicher
    • 1
  1. 1.Genzyme CorporationBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine
  • Print ISBN 978-1-60761-967-3
  • Online ISBN 978-1-60761-968-0
  • Buy this book on publisher's site