Animal Models of Drug Addiction

  • Mary C.¬†Olmstead

Part of the Neuromethods book series (NM, volume 53)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Behavioral Paradigms

    1. Front Matter
      Pages 1-1
    2. Styliani Vlachou, Athina Markou
      Pages 3-56
    3. Leigh V. Panlilio
      Pages 57-81
    4. Francesco Leri
      Pages 83-100
    5. Robert E. Sorge, Paul B. S. Clarke
      Pages 101-132
    6. Friedbert Weiss
      Pages 133-166
    7. Christopher L. Cunningham, Peter A. Groblewski, Charlene M. Voorhees
      Pages 167-189
    8. Jessica A. Loweth, Paul Vezina
      Pages 191-205
    9. Stephanie D. Hancock, Mary C. Olmstead
      Pages 207-234
  3. Modeling Stages of Drug Addiction in Animals

    1. Front Matter
      Pages 235-235
    2. Marilyn E. Carroll, Richard A. Meisch
      Pages 237-265
    3. Serge H. Ahmed
      Pages 267-292
    4. Aldo Badiani, Daniele Caprioli, Arianna Testa, Maria Teresa De Luca, Michele Celentano
      Pages 293-309
    5. Jeffrey W. Grimm
      Pages 311-336
    6. David Belin, Daina Economidou, Yann Pelloux, Barry J. Everitt
      Pages 337-378
    7. Andrea Bari, Trevor W. Robbins, Jeffrey W. Dalley
      Pages 379-401
    8. Herbert E. Covington III, Klaus A. Miczek
      Pages 403-430
    9. Alasdair M. Barr, Heidi N. Boyda, Ric M. Procyshyn
      Pages 431-459
    10. Suzanne Erb, Franca Placenza
      Pages 461-479
  4. Back Matter
    Pages 481-484

About this book


Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.


Behavioural pharmacology Clinical symptomatology Compulsive drug taking Neural systems Therapeutic tools Withdrawal and relapse

Editors and affiliations

  • Mary C.¬†Olmstead
    • 1
  1. 1., Department of PsychologyQueen's UniversityKingstonCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-933-8
  • Online ISBN 978-1-60761-934-5
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site