Book Volume 662 2010

Systems Biology in Drug Discovery and Development

Methods and Protocols

Editors:

ISBN: 978-1-60761-799-0 (Print) 978-1-60761-800-3 (Online)

Table of contents (17 protocols)

  1. Front Matter

    Pages i-xii

  2. Methodologies of Systems Biology in Drug Discovery and Development

    1. Front Matter

      Pages 1-1

    2. No Access

      Protocol

      Pages 3-28

      Proteomics and Systems Biology: Application in Drug Discovery and Development

    3. No Access

      Protocol

      Pages 29-58

      Systems Biology Approaches and Tools for Analysis of Interactomes and Multi-target Drugs

    4. No Access

      Protocol

      Pages 59-78

      Systems Biology “On-the-Fly”: SILAC-Based Quantitative Proteomics and RNAi Approach in Drosophila melanogaster

    5. No Access

      Protocol

      Pages 79-95

      Systems Biology of Cell Behavior

    6. No Access

      Protocol

      Pages 97-120

      Computational Modeling in Systems Biology

    7. No Access

      Protocol

      Pages 121-147

      An Introduction to Gaussian Bayesian Networks

    8. No Access

      Protocol

      Pages 149-165

      Derivation of Large-Scale Cellular Regulatory Networks from Biological Time Series Data

    9. No Access

      Protocol

      Pages 167-178

      Translational Bioinformatics and Systems Biology Approaches for Personalized Medicine

  3. Systems Biology Methods for Disease Treatment and Translational Medicine

    1. Front Matter

      Pages 179-179

    2. No Access

      Protocol

      Pages 181-201

      Systems Biology and Inflammation

    3. No Access

      Protocol

      Pages 203-220

      Immunoinformatics and Systems Biology Methods for Personalized Medicine

    4. No Access

      Protocol

      Pages 221-243

      Systems Biology Approaches to the Study of Cardiovascular Drugs

    5. No Access

      Protocol

      Pages 245-263

      Cancer Systems Biology

    6. No Access

      Protocol

      Pages 265-283

      Systemic Lupus Erythematosus: From Genes to Organ Damage

    7. No Access

      Protocol

      Pages 285-302

      Systems Biology of Influenza: Understanding Multidimensional Interactions for Personalized Prevention and Treatment

    8. No Access

      Protocol

      Pages 303-316

      Methods in Systems Biology of Experimental Methamphetamine Drug Abuse

    9. No Access

      Protocol

      Pages 317-329

      Systems Biology and Theranostic Approach to Drug Discovery and Development to Treat Traumatic Brain Injury

  4. Erratum

    1. Protocol

      Pages E1-E1

      Erratum to: Cancer Systems Biology

  5. Back Matter

    Pages 331-337