Nitrite and Nitrate in Human Health and Disease

  • Nathan S. Bryan
  • Joseph Loscalzo

Part of the Nutrition and Health book series (NH)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Basic Biochemistry, Metabolism, and Physiology

    1. Front Matter
      Pages 1-1
    2. Nathan S. Bryan, Joseph Loscalzo
      Pages 3-7
    3. Mark Gilchrist, Nigel Benjamin
      Pages 9-19
    4. Jon O. Lundberg, Eddie Weitzberg, Sruti Shiva, Mark T. Gladwin
      Pages 21-48
    5. Andrew L. Milkowski
      Pages 49-65
  3. Food and Environmental Exposures to Nitrite and Nitrate

  4. Nitrite and Nitrate in Therapeutics and Disease

    1. Front Matter
      Pages 167-167
    2. Nathan S. Bryan, Jack R. Lancaster Jr.
      Pages 169-186
    3. Kenneth D. Bloch, Andrea U. Steinbicker, Lisa K. Lohmeyer, Rajeev Malhotra
      Pages 187-205
    4. Nathaniel A. Page, Ho-Leung Fung
      Pages 207-224
    5. Madhav Lavu, Susheel Gundewar, David J. Lefer
      Pages 225-246
    6. David M. Klurfeld
      Pages 263-278
    7. Nathan S. Bryan, Joseph Loscalzo
      Pages 279-291
  5. Back Matter
    Pages 293-306

About this book


Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body.  Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate.  The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing.  This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government.  Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.


Flavanols NO Homeostasis Nitric Oxide Nitric Oxide Pathway Nitrite Therapy Nitrovasodilators Polyphenols

Editors and affiliations

  • Nathan S. Bryan
    • 1
  • Joseph Loscalzo
    • 2
  1. 1.Health Science Center, Houston, Inst. Molecular MedicineUniversity of TexasHoustonUSA
  2. 2.Brigham & Women's HospitalHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-60761-615-3
  • Online ISBN 978-1-60761-616-0
  • Buy this book on publisher's site