Drug Delivery to the Central Nervous System

  • Kewal K. Jain

Part of the Neuromethods book series (NM, volume 45)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Kewal K. Jain
    Pages 1-13
  3. Ji-Ming Feng, Philip C.W. Lui, Jian Yi Li
    Pages 15-34
  4. Kiril Lanevskij, Pranas Japertas, Remigijus Didziapetris, Alanas Petrauskas
    Pages 63-83
  5. Raghu Raghavan
    Pages 85-135
  6. Shawn Belverud, Alon Mogilner, Michael Schulder
    Pages 137-153
  7. Ibrahim A. Alsarra, Amel Y. Hamed, Fars K. Alanazi, Gamal M. El Maghraby
    Pages 175-203
  8. Birgit Neuhuber, Itzhak Fischer
    Pages 219-232
  9. Ken A. Witt, Patrick T. Ronaldson, Karin E. Sandoval, Thomas P. Davis
    Pages 233-247
  10. Yongting Wang, Falei Yuan, Guo-Yuan Yang
    Pages 261-276
  11. Sin-Soo Jeun, Seong Muk Kim, Jung Yeon Lim, Chung Heon Ryu
    Pages 277-290
  12. Dale Ding, Charles W. Kanaly, Martin L. Brady, Stephan Mittermeyer, Raghu Raghavan, John H. Sampson
    Pages 291-318
  13. Back Matter
    Pages 319-321

About this book


Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results.

Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.


Blood-brain barrier - BBB CNS Nervous System Neurological disorders Therapeutics gene therapy

Editors and affiliations

  • Kewal K. Jain
    • 1
  1. 1.Jain PharmaBiotechBaselSwitzerland

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-528-6
  • Online ISBN 978-1-60761-529-3
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site