Myeloproliferative Neoplasms

Biology and Therapy

  • Srdan Verstovsek
  • Ayalew Tefferi

Part of the Contemporary Hematology book series (CH)

Table of contents

  1. Front Matter
    Pages i-x
  2. Omar Abdel-Wahab, Ross L. Levine
    Pages 39-68
  3. John T. Reilly
    Pages 69-83
  4. Francisco Cervantes, Juan-Carlos Hernández-Boluda
    Pages 85-96
  5. Guido Finazzi, Tiziano Barbui
    Pages 97-115
  6. Daniella M. B. Kerbauy, H. Joachim Deeg
    Pages 139-150
  7. Fabio P. S. Santos, Srdan Verstovsek
    Pages 151-167
  8. Back Matter
    Pages 223-228

About this book

Introduction

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.

Keywords

Disorders Eosinophilic JAK2 Leukemia MPL Mastocytosis Mutation Myelofibrosis Myeloid Myeloproliferative Neoplasms Polycythemia Throbocythemia

Editors and affiliations

  • Srdan Verstovsek
    • 1
  • Ayalew Tefferi
    • 2
  1. 1.M.D. Anderson Cancer Center, Dept. LeukemiaUniversity of TexasHoustonUSA
  2. 2.Dept. Internal Medicine, Div. HematologyMayo ClinicRochesterUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-266-7
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine
  • Print ISBN 978-1-60761-265-0
  • Online ISBN 978-1-60761-266-7
  • About this book