Primary Central Nervous System Tumors

Pathogenesis and Therapy

  • Andrew D. Norden
  • David A. Reardon
  • Patrick C. Y. Wen

Part of the Current Clinical Oncology book series (CCO)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. General Principles

    1. Front Matter
      Pages 1-1
    2. Christine Lu-Emerson, Andrew D. Norden
      Pages 3-25
    3. Howard Colman, Ken Aldape
      Pages 27-44
    4. Christopher M. Taylor, Claire M. Sauvageot, Patrick Y.C. Wen, Charles D. Stiles
      Pages 45-53
    5. Jan Drappatz, Patrick Y.C. Wen
      Pages 55-84
    6. Nicholas Butowski, Susan Chang
      Pages 85-102
    7. Derek R. Johnson, Jonathan B. Ashman, Paul D. Brown, Daniel H. Lachance, Jan C. Buckner
      Pages 103-141
    8. Jeffrey S. Wefel, Terri A. Armstrong, Sadhna Kohli
      Pages 143-170
  3. Gliomas

    1. Front Matter
      Pages 171-171
    2. Jonathan H. Sherman, David Weintraub, M. Beatriz S. Lopes, David Schiff
      Pages 173-194
    3. Sith Sathornsumetee, David A. Reardon
      Pages 195-232
    4. Jacoline E.C. Bromberg, Martin J. van den Bent
      Pages 233-248
    5. Mark R. Gilbert, Roberta Ruda, Riccardo Soffietti
      Pages 249-262
  4. Other Tumor Types

    1. Front Matter
      Pages 283-283
    2. Michelle A. Lee, Nathan J. Robison, Susan N. Chi, Sridharan Gururangan, Mark W. Kieran
      Pages 285-332
    3. Elizabeth R. Gerstner, Tracy T. Batchelor
      Pages 333-353
    4. Marc C. Chamberlain
      Pages 355-375
    5. Gabriel Zada, Whitney Woodmansee, Ursula Kaiser, Edward R. Laws
      Pages 377-400
    6. Mohamed E. Abazeed, Frederick G. Barker II, Scott R. Plotkin, Jay S. Loeffler, Helen A. Shih
      Pages 401-413
    7. Alba A. Brandes, Enrico Franceschi
      Pages 415-433
    8. Harry C. Brastianos, Priscilla K. Brastianos, Jaishri Blakeley
      Pages 435-455
    9. Mikael L. Rinne, Scott R. Plotkin
      Pages 457-497
    10. Erik J. Uhlmann, Andrew D. Norden
      Pages 499-528
    11. Camilo A. Molina, Ziya L. Gokaslan, Daniel M. Sciubba
      Pages 529-547
  5. Back Matter
    Pages 549-568

About this book


This comprehensive, yet practical, text is a ready collection of the most up-to-date information on primary CNS tumors. Authored by a carefully selected group of the world’s leading clinicians and scientists, the book is divided into three sections. The opening chapters cover general principles, including epidemiology, pathogenesis, tumor stem cells, supportive care, complications of therapy, and quality of life. The remaining two sections are comprised of treatment-oriented chapters covering the spectrum of gliomas and rarer tumor types. Each of these chapters presents multi-disciplinary therapeutic approaches and addresses specific disease concerns. Throughout, the authors incorporate the cutting-edge advances in molecular biology and genomics that are revolutionizing neuro-oncology. The result is an important clinical resource which provides evidence-based data and interpretation essential to intelligent therapeutic decision making.


Astrocytoma Brain Tumor CNS lymphoma Chemotherapy Ependymoma Glioma Hemangioblastoma Medulloblastoma Meningioma Neurosurgery Oligodendogliomas Pituitary Adenoma Radiation Therapy Schwannoma

Editors and affiliations

  • Andrew D. Norden
    • 1
  • David A. Reardon
    • 2
  • Patrick C. Y. Wen
    • 3
  1. 1.Dana-Farber Cancer InstituteHarvard Medical SchoolBostonUSA
  2. 2.Departments of Surgery and PediatricsDuke University Medical CenterDurhamUSA
  3. 3.Dana-Farber Cancer InstituteHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-60761-165-3
  • Online ISBN 978-1-60761-166-0
  • Buy this book on publisher's site