Table of contents

  1. Front Matter
    Pages i-xi
  2. Clinical, Physiology and Genetics Changes in Heart Failure

    1. Front Matter
      Pages 1-1
    2. José Marín-García
      Pages 3-13
    3. José Marín-García
      Pages 23-42
  3. Biochemical and Molecular Changes in Heart Failure

    1. Front Matter
      Pages 44-44
  4. The Mitochondrial Organelle and the Heart

    1. Front Matter
      Pages 72-72
  5. Experimental Models of Heart Failure

    1. Front Matter
      Pages 108-108
    2. José Marín-García
      Pages 109-127
  6. Signaling, Stress and Cellular Changes in Heart Failure

  7. Peripheral Changes and Co-morbid Conditions in Heart Failure

    1. Front Matter
      Pages 234-234
    2. José Marín-García
      Pages 257-270

About this book

Introduction

Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease.  An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies.

Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF.  Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. Heart Failure: Bench to Bedside thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers.

Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.

Keywords

Bioenergetics Cardiac Drug Therapy Cell Biology Gene Therapy Genetics Heart Failure Left Ventricular Assist Device Molecualr Medicine Molecular Biology cardiac function cardiovascular

Authors and affiliations

  • José Marín-García
    • 1
  1. 1.Neuromuscular InstituteMolecular Cardiology &Highland ParkUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-147-9
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine
  • Print ISBN 978-1-60761-146-2
  • Online ISBN 978-1-60761-147-9
  • About this book