Brain Hypoxia and Ischemia

with Special Emphasis on Development

  • Gabriel G. Haddad
  • Shan Ping Yu

Part of the Contemporary Clinical Neuroscience book series (CCNE)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Ion Channels, Transporters and Excitotoxicity

  3. Reactive Oxygen Species, and Gene Expression to Behavior

    1. Joseph C. LaManna, Paola Pichiule, Kui Xu, Juan Carlos Chávez
      Pages 213-223
    2. Zezong Gu, Jiankun Cui, Stuart A. Lipton
      Pages 225-238
    3. Laura L. Dugan, M. Margarita Behrens, Sameh S. Ali
      Pages 239-254
    4. Gregg L. Semenza
      Pages 277-288
  4. Back Matter
    Pages 335-343

About this book


Brain Hypoxia and Ischemia

Gabriel G. Haddad, M.D. and Shan Ping Yu, M.D., Ph.D., Editors

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development.

This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

Gabriel G. Haddad, M.D. is Professor of Pediatrics and Neuroscience and Chair of the Department of Pediatrics at the University of California, San Diego. He is also Physician-in-Chief at Rady Children’s Hospital in San Diego.

Shan Ping Yu, M.D., Ph.D. is Professor of Anesthesiology at Emory University in Atlanta, GA.


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Editors and affiliations

  • Gabriel G. Haddad
    • 1
    • 2
  • Shan Ping Yu
    • 3
  1. 1.University of CaliforniaSan Diego
  2. 2.Rady Children's HospitalSan Diego
  3. 3.Emory UniversityAtlanta

Bibliographic information