Biosensors and Biodetection

Methods and Protocols: Electrochemical and Mechanical Detectors, Lateral Flow and Ligands for Biosensors

  • Avraham Rasooly
  • Keith E. Herold

Part of the Methods in Molecular Biology™ book series (MIMB, volume 504)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Mechanical Detectors

    1. Carsten Teller, Jan Halámek, Alexander Makower, Frieder W. Scheller
      Pages 3-22
    2. Sara Tombelli, Alessandra Bini, Maria Minunni, Marco Mascini
      Pages 23-36
    3. Mar Álvarez, Laura G. Carrascosa, Kiril Zinoviev, Jose A. Plaza, Laura M. Lechuga
      Pages 51-71
  3. Electrochemical Detectors

    1. Ilaria Palchetti, Serena Laschi, Marco Mascini
      Pages 115-126
    2. María Teresa Castañeda, Salvador Alegret, Arben Merkoçi
      Pages 127-143
    3. Alfredo de la Escosura-Muñiz, Adriano Ambrosi, Salvador Alegret, Arben Merkoçi
      Pages 145-155
    4. A. González-Cortés, P. Yáñez-Sedeño, J. M. Pingarrón
      Pages 157-166
  4. Lateral Flow

    1. Gaiping Zhang, Junqing Guo, Xuannian Wang
      Pages 169-183
    2. Alexander Volkov, Michael Mauk, Paul Corstjens, R. Sam Niedbala
      Pages 217-235
    3. Shuo Wang, Can Zhang, Yan Zhang
      Pages 237-252
  5. Ligands

    1. Juan E. Diaz, Li-Mei C. Yang, Jorge A. Lamboy, Reginald M. Penner, Gregory A. Weiss
      Pages 255-274
    2. Michael J. McGuire, Shunzi Li, Kathlynn C. Brown
      Pages 291-321
    3. Sarah A. Richman, David M. Kranz, Jennifer D. Stone
      Pages 323-350
  6. Protein and DNA Preparation

    1. Lisa C. Shriver-Lake, Paul T. Charles, Chris R. Taitt
      Pages 419-440
    2. Keith E. Herold, Nikolay Sergeev, Andriy Matviyenko, Avraham Rasooly
      Pages 441-458
  7. Back Matter
    Pages 459-464

About this book


Biosensors combine biological recognition elements and signal conversion elements into a biodetection system. They have been developed for a wide variety of biodetection applications, offering the advantages of increased speed and ease of use compared to traditional detection methods. In Biosensors and Biodetection: Methods and Protocols, leading experts describe the major technologies in the field in extensive technical detail, allowing readers both to understand the technology and to construct similar devices. Volume 2: Electrochemical and Mechanical Detectors, Lateral Flow and Ligands for Biosensors focuses on direct measurement sensors, indirect methods, ligands, and related technologies, including methods involving electrochemical detectors, recognition ligands, antibodies, aptamers, and peptides, amongst many other subjects. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to the topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and Notes sections, which highlight tips on troubleshooting and avoiding known pitfalls.

Comprehensive and up-to-date, Biosensors and Biodetection: Methods and Protocols is an ideal, user-friendly guide to this vital, versatile technology and a perfect tool for those who wish to further the field.


Biochemical reactions Biosensor DNA Electrochemical detectors Lateral flow Ligands Mechanical detectors Piezoelectric biosensors Protein and DNA preparation RNA

Editors and affiliations

  • Avraham Rasooly
    • 1
    • 2
  • Keith E. Herold
    • 3
  1. 1.FDA Center for Devices and Radiological HealthSilver SpringUSA
  2. 2.National Cancer InstituteBethesdaUSA
  3. 3.Fischell Department of BioengineeringUniversity of MarylandCollege ParkUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-568-2
  • Online ISBN 978-1-60327-569-9
  • Series Print ISSN 1064-3745
  • Buy this book on publisher's site