Iron Physiology and Pathophysiology in Humans

  • Gregory J. Anderson
  • Gordon D. McLaren

Part of the Nutrition and Health book series (NH)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Cellular Iron Metabolism

    1. Front Matter
      Pages 1-1
    2. Surjit Kaila Srai, Paul Sharp
      Pages 3-25
    3. Martina U. Muckenthaler, Roland Lill
      Pages 27-50
    4. Tracey A. Rouault
      Pages 51-62
  3. Iron Physiology

    1. Front Matter
      Pages 79-79
    2. Weng-In Leong, Bo Lönnerdal
      Pages 81-99
    3. Andrew T. McKie, Robert J. Simpson
      Pages 101-116
    4. Ross M. Graham, Anita C. G. Chua, Debbie Trinder
      Pages 117-139
    5. Ann Smith
      Pages 141-171
    6. Tomas Ganz, Sophie Vaulont
      Pages 173-190
    7. Prem Ponka, Alex D. Sheftel
      Pages 191-209
    8. Günter Weiss
      Pages 211-231
    9. Hal Drakesmith, Graça Porto, Maria de Sousa
      Pages 233-248
  4. Disorders of Iron Homeostasis: Anemias

    1. Front Matter
      Pages 249-249
    2. Barry Skikne, Chaim Hershko
      Pages 251-282
    3. John L. Beard, Carrie Durward
      Pages 283-302
  5. Disorders of Iron Homeostasis: Iron Overload and Related Conditions

    1. Front Matter
      Pages 343-343
    2. Yves Deugnier, Bruno Turlin
      Pages 345-355
    3. Richard G. Ruddell, Grant A. Ramm
      Pages 357-383
    4. Richard Skoien, Lawrie W. Powell
      Pages 385-398
    5. Daniel F. Wallace, V. Nathan Subramaniam
      Pages 399-416
    6. Carole Beaumont
      Pages 417-439
    7. Darrell H. G. Crawford, Linda M. Fletcher, Kris V. Kowdley
      Pages 441-454
    8. Sarah J. Texel, Xueying Xu, Sokhon Pin, Z. Leah Harris
      Pages 455-476
    9. Sergei Nekhai, Victor R. Gordeuk
      Pages 477-495
  6. Clinical Diagnosis and Therapy

    1. Front Matter
      Pages 497-497
    2. Mark Worwood
      Pages 499-528
    3. James C. Barton, Pauline L. Lee, Corwin Q. Edwards
      Pages 529-565
    4. Robert C. Hider, Yong Min Ma
      Pages 567-590
    5. John B. Porter, Chaim Hershko
      Pages 591-627
  7. Model Systems for Studying Iron Homeostasis

    1. Front Matter
      Pages 629-629
    2. Robert S. Britton, Bruce R. Bacon, Robert E. Fleming
      Pages 631-652
    3. Caroline C. Philpott
      Pages 653-667
    4. Paula Goodman Fraenkel
      Pages 669-683
  8. Back Matter
    Pages 685-703

About this book


Iron Physiology and Pathophysiology in Humans provides health professionals in many areas of research and practice with the most up-to-date and well-referenced volume on the importance of iron as a nutrient and its role in health and disease.  This important new volume is the benchmark in the complex area of interrelationships between the essentiality of iron, its functions throughout the body, including its critical role in erythropoiesis, the biochemistry and clinical relevance of iron-containing enzymes and other molecules involved in iron absorption, transport and metabolism, the importance of optimal iron status on immune function, and links between iron and the liver, heart,  brain and other organs.  Moreover, the interactions between genetic and environmental factors and the numerous co-morbidities seen with both iron deficiency and iron overload in populations at risk are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions.

Key features of the volume include an in-depth index and recommendations and practice guidelines are included in relevant chapters. The volume contains more than 100 detailed tables and informative figures and up-to-date references that provide the reader with excellent sources of information about the critical role of iron nutrition, optimal iron status and the adverse clinical consequences of altered iron homeostasis.  Iron Physiology and Pathophysiology in Humans is an excellent new text as well as the most authoritative resource in the field.


Anemias Cellular Metabolism Cellular Metabolism Homeostasis Iron Iron Iron Homeostasis Iron Overload Pathophysiology Pathophysiology Physiology Physiology

Editors and affiliations

  • Gregory J. Anderson
    • 1
  • Gordon D. McLaren
    • 2
  1. 1.Bancroft CentreQueensland Institute of Medical ResearchBrisbaneAustralia
  2. 2.Dept. Medicine &, Chao Family Comprehensive Cancer Ctr.University of California, IrvineLong BeachUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-60327-484-5
  • Online ISBN 978-1-60327-485-2
  • Buy this book on publisher's site