Structure, Function and Applications

  • Jonathan M. Keith

Part of the Methods in Molecular Biology™ book series (MIMB, volume 453)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Structures

    1. Nicholas R. Markham, Michael Zuker
      Pages 3-31
    2. Bissan Al-Lazikani, Emma E. Hill, Veronica Morea
      Pages 33-85
    3. Nicholas Hamilton, Thomas Huber
      Pages 87-104
    4. Rune Matthiesen, Ole N. Jensen
      Pages 105-122
    5. Russell L. Marsden, Christine A. Orengo
      Pages 123-146
  3. Inferring Function

    1. Richard D. Emes
      Pages 149-168
    2. Shailesh V. Date
      Pages 169-180
    3. Shailesh V. Date, José M. Peregrín-Alvarez
      Pages 201-216
    4. Dario Boffelli
      Pages 217-231
    5. Albin Sandelin
      Pages 233-244
    6. Joaquín Dopazo, Fátima Al-Shahrour
      Pages 245-255
    7. Nicolas Goffard, Georg Weiller
      Pages 257-265
    8. Insuk Lee, Edward M. Marcotte
      Pages 267-278
  4. Applications and Disease

    1. Claudio Lottaz, Dennis Kostka, Florian Markowetz, Rainer Spang
      Pages 281-296
    2. Mario Falchi
      Pages 297-326
    3. Jens Auer, Jürgen Bajorath
      Pages 327-347
    4. Hanna Eckert, Jürgen Bajorath
      Pages 349-362
    5. Mou'ath Hourani, Regina Berretta, Alexandre Mendes, Pablo Moscato
      Pages 379-392
  5. Analytical and Computational Methods

    1. Falk Hüffner, Rolf Niedermeier, Sebastian Wernicke
      Pages 395-421
    2. Geoffrey J. McLachlan, Richard W. Bean, Shu-Kay Ng
      Pages 423-439
    3. Falk Schreiber
      Pages 441-450
    4. Mark Halling-Brown, Adrian J. Shepherd
      Pages 451-470
    5. Andrew B. Clegg, Adrian J. Shepherd
      Pages 471-491
  6. Back Matter
    Pages 493-502

About this book


Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems.  Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and "meta-methods" for developers of bioinformatics algorithms.  As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Comprehensive and cutting-edge, Bioinformatics: Volume II: Structure, Function and Applications is an ideal reference for all scientists involved with the ever-growing array of data in the expanding field of life science.


Computational diagnostics Databases Microarray expression data Phylogenetics Proteomics RNA Radiologieinformationssystem Sequence analysis Sequence data bioinformatics classification coding gene expression genes hybridization

Editors and affiliations

  • Jonathan M. Keith
    • 1
  1. 1.School of Mathematical SciencesQueensland University of TechnologyBrisbaneAustralia

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-428-9
  • Online ISBN 978-1-60327-429-6
  • Series Print ISSN 1064-3745
  • Buy this book on publisher's site