Characterization of Nanoparticles Intended for Drug Delivery

  • Scott E. McNeil

Part of the Methods in Molecular Biology book series (MIMB, volume 697)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Introduction and Discussion

  3. Assays to Determine Physical and Chemical Properties

    1. Front Matter
      Pages 33-33
    2. Uma Ramalinga, Jeffrey D. Clogston, Anil K. Patri, John T. Simpson
      Pages 53-61
    3. Jeffrey D. Clogston, Anil K. Patri
      Pages 63-70
    4. Jaroslaw Grobelny, Frank W. DelRio, Namboodiri Pradeep, Doo-In Kim, Vincent A. Hackley, Robert F. Cook
      Pages 71-82
    5. Kunio Nagashima, Jiwen Zheng, David Parmiter, Anil K. Patri
      Pages 83-91
    6. Jiwen Zheng, Kunio Nagashima, David Parmiter, Jason de la Cruz, Anil K. Patri
      Pages 93-99
    7. Jeffrey D. Clogston, Anil K. Patri
      Pages 101-108
    8. Jeffrey D. Clogston, Anil K. Patri
      Pages 109-117
  4. Assays for Sterility

    1. Front Matter
      Pages 119-119
    2. Timothy M. Potter, Marina A. Dobrovolskaia
      Pages 131-134
  5. Assays for In Vitro Detection and Quantitation

    1. Front Matter
      Pages 135-135
    2. Parag Aggarwal, Marina A. Dobrovolskaia
      Pages 137-143
    3. King C. Chan, Timothy D. Veenstra, Haleem J. Issaq
      Pages 145-153

About this book


In recent years, there have been many exciting breakthroughs in the application of nanotechnology to medicine. In Characterization of Nanoparticles Intended for Drug Delivery, expert researchers explore the latest advances in the field, providing a set of basic methods for the characterization of nanomaterials for medical use. Chapters provide methods to characterize the physiochemical properties (size, aggregation, and surface chemistry) and in vitro immunological and biological characteristics of nanomaterials. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and informative, Characterization of Nanoparticles Intended for Drug Delivery is an essential survey of methods that are crucial to the preclinical characterization of nanomedicines.


Assays for sterility Assays for toxicity Atomic force microscopy Nanomedicine Physicochemical properties Thin layer chromatography

Editors and affiliations

  • Scott E. McNeil
    • 1
  1. 1.SAIC-Frederick, Inc., Nanotechnology Characterization LabNational Cancer Institute at FrederickFrederickUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-197-4
  • Online ISBN 978-1-60327-198-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book