Telomerase Inhibition

Strategies and Protocols

  • Lucy G. Andrews
  • Trygve O. Tollefsbol

Part of the Methods in Molecular Biology™ book series (MIMB, volume 405)

Table of contents

  1. Front Matter
    Pages i-x
  2. Lucy G. Andrews, Trygve O. Tollefsbol
    Pages 1-8
  3. Serene R. Lai, Lucy G. Andrews, Trygve O. Tollefsbol
    Pages 23-29
  4. Serene R Lai, Lucy G Andrews, Trygve O Tollefsbol
    Pages 31-37
  5. Amanda P. Cunningham, Lucy G. Andrews, Trygve O. Tollefsbol
    Pages 39-46
  6. He Li, Indzi Katik, Jun-Ping Liu
    Pages 61-86
  7. Yi-Yuan Huang, Jing-Wen Shih, Jing-Jer Lin
    Pages 87-96
  8. Shang Li, Mehdi Nosrati, Mohammed Kashani-Sabet
    Pages 113-131
  9. Tomokazu Ohishi, Takashi Tsuruo, Hiroyuki Seimiya
    Pages 133-146
  10. Dakang Xu, He Li, Jun-Ping Liu
    Pages 147-165
  11. Elke Kleideiter, Kamilla Piotrowska, Ulrich Klotz
    Pages 167-180
  12. Tetsuzo Tauchi, Junko H. Ohyashiki, Kazuma Ohyashiki
    Pages 181-189
  13. Back Matter
    Pages 191-193

About this book

Introduction

Due in part to the selective nature of telomerase inhibition as an anticancer approach, the field has expanded considerably in the past decade. The recent advances in methods of telomerase inhibition encompass many different areas of research including molecular biology, cell biology, biochemistry, oncology and gerontology. Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition. Leaders in the field provide recently developed methods that have widespread application such as targeting the telomerase holoenzyme, its RNA template and other elements associated with telomerase activity. Additional methods involving the screening of telomerase inhibitors and telomerase inhibition combined with other chemotherapeutic agents are presented. This text, on the cutting edge of the field, will provide investigators with the most recent methods applied to the expanding field of telomerase inhibition.

Keywords

Endoplasmatisches Reticulum Nucleotide RNA Telomere biochemistry cell biology cell lines molecular biology

Editors and affiliations

  • Lucy G. Andrews
    • 1
  • Trygve O. Tollefsbol
    • 1
  1. 1.Department of BiologyUniversity of Alabama at BirminghamBirmingham

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60327-070-0
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-683-2
  • Online ISBN 978-1-60327-070-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book