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Dynamic Brain Imaging

Multi-Modal Methods and In Vivo Applications

  • Book
  • © 2009

Overview

Editors:
  1. Fahmeed Hyder

    1. Yale University, New Haven, USA

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  • Provides a balanced emphasis on methods and applications that even specialists within various functional imaging fields will find useful
  • Contains a review of developments in technical features of dynamic multi-modal imaging and analytical tools for characterization of dynamic signals
  • Includes novel multi-modal applications in neuroimaging to epilepsy, with state-of-the-art demonstrations of increased sensitivity and specificity of detection
  • Examines examples of dynamic functional imaging of multiple brain areas (e.g., cerebral cortex, olfactory bulb, retina) using cutting-edge multi-modal techniques

Part of the book series: Methods in Molecular Biology (MIMB, volume 489)

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Table of contents (15 protocols)

  1. Alternate Magnetic Resonance Methods

    1. Advanced In Vivo Heteronuclear MRS Approaches for Studying Brain Bioenergetics Driven by Mitochondria

      • Xiao-Hong Zhu, Fei Du, Nanyin Zhang, Yi Zhang, Hao Lei, Xiaoliang Zhang et al.
      Pages 317-357

  2. Back Matter

    Pages 359-363
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Keywords

About this book

If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more. This book will help users learn to decipher the dynamic imaging data that will be critical to our future understanding of complex brain functions. In recent years, there have been unprecedented methodological advancements in the imaging of brain activity. These techniques allow the measurement of everything from neural activity (e.g., membrane potential, ion ?ux, neurotransmitter ?ux) to energy metabolism (e.g., glucose consumption, oxygen consumption, creatine kinase ?ux) and functional hyperemia (e.g., blood ?ow, volume, oxygenation). This book deals with a variety of magnetic resonance, electrophysiology, and optical methods that are often used to measure some of these dynamic processes. All chapters were written by leading experts, spanning three continents, specializing in state-of-the-art methods. Brie?y, the book has ?ve sections. In the introductory section, there are two chapters; the ?rst one contains a brief pre- ble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data. The second section has four chapters and delves into a wide range of optical imaging methods. I am privileged to include a chapter from Lawrence B. Cohen, considered by many to be the authority on optical imaging and spectroscopy, both in vitro and in vivo [Cohen LB (1973) Physiol Rev.

Reviews

From the reviews:

"The title follows a similar review of Dynamic Brain Imaging, with an emphasis on methods and protocols. The stated goal of this book is to ‘… help users learn to decipher the dynamic imaging data.’ … Overall … chapters were well written and accomplished their intended goal of educating the reader about the various dynamic imaging methodologies at various stages of development. … In summary, this review of multimodal in vivo brain imaging methods provides a nice compilation of manuscripts … ." (American Journal of Neuroradiology, Vol. 30, May, 2009)

Editors and Affiliations

  • Yale University, New Haven, USA

    Fahmeed Hyder

Bibliographic Information

  • Book Title: Dynamic Brain Imaging

  • Book Subtitle: Multi-Modal Methods and In Vivo Applications

  • Editors: Fahmeed Hyder

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-59745-543-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2009

  • Hardcover ISBN: 978-1-934115-74-9Published: 23 October 2008

  • Softcover ISBN: 978-1-62703-881-2Published: 03 November 2014

  • eBook ISBN: 978-1-59745-543-5Published: 08 October 2008

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XVIII, 379

  • Topics: Neurology, Neurosciences, Neurochemistry, Diagnostic Radiology

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