Dynamic Brain Imaging

Multi-Modal Methods and In Vivo Applications

  • Fahmeed Hyder

Part of the METHODS IN MOLECULAR BIOLOGY™ book series (MIMB, volume 489)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Fahmeed Hyder
      Pages 3-21
  3. Optical Imaging

    1. Front Matter
      Pages 41-41
    2. Ryota Homma, Bradley J. Baker, Lei Jin, Olga Garaschuk, Arthur Konnerth, Lawrence B. Cohen et al.
      Pages 43-79
    3. Pascale Tiret, Emmanuelle Chaigneau, Jérôme Lecoq, Serge Charpak
      Pages 81-91
    4. Xiaohai Wang, Takahiro Takano, Maiken Nedergaard
      Pages 93-109
  4. Electrophysiology

    1. Front Matter
      Pages 133-133
    2. Nandakumar S. Narayanan, Mark Laubach
      Pages 135-165
    3. Andreas A. Ioannides
      Pages 167-188
    4. Joshua E. Motelow, Hal Blumenfeld
      Pages 189-209
  5. Functional Magnetic Resonance Imaging (fMRI)

    1. Front Matter
      Pages 211-211
    2. Basavaraju G. Sanganahalli, Christopher J. Bailey, Peter Herman, Fahmeed Hyder
      Pages 213-242
    3. Yul-Wan Sung, Seiji Ogawa
      Pages 243-254
    4. Bharat B. Biswal, Sridhar S. Kannurpatti
      Pages 255-274
  6. Alternate Magnetic Resonance Methods

    1. Front Matter
      Pages 275-275
    2. Allen W. Song, Trong-Kha Truong, Marty Woldorff
      Pages 297-315
    3. Xiao-Hong Zhu, Fei Du, Nanyin Zhang, Yi Zhang, Hao Lei, Xiaoliang Zhang et al.
      Pages 317-357
  7. Back Matter
    Pages 359-363

About this book


The developing of in vivo neuroscience techniques is rapidly improving the specificity and sensitivity of measurements of brain function. However, despite improvements in individual methods, it is becoming increasingly clear that the most effective research approaches will be multi-modal. Thus, it is the researchers who are familiar with many in vivo techniques who will be able to make the most substantial contributions to our understanding of dynamic brain function.

In Dynamic Brain Imaging: Multi-Modal Methods and In Vivo Applications, leading experts specializing in magnetic resonance, electrophysiology, and optical imaging methods explain basic principles of their respective techniques and demonstrate their power in depicting functional activation patterns en route to a basic understanding of the dynamic processes underlying various neuroimaging signals. The novel results, from various species, provide a new understanding of dynamics of neural activity that span a wide spatiotemporal range. Numerous cutting-edge applications are used as examples to illustrate enticing possibilities of combining techniques toward studies of normal function and disease. Exclusive examples of dynamic functional imaging of the cerebral cortex, olfactory bulb, and retina are used to demonstrate the effectiveness of each method for applications to the neurosciences. State-of-the-art techniques described include multi-photon optical imaging, multi-array electrical recordings, heteronuclear magnetic resonance spectroscopy and functional magnetic resonance imaging.

Up-to-date and user-friendly, Dynamic Brain Imaging: Multi-Modal Methods and In Vivo Applications is designed to be accessible to both specialist neurophysiologists and general neuroscientists. It reviews the fundamental, theoretical, and practical principles of magnetic resonance, electrophysiology, and optical methods as applied in the neurosciences and shows how these tools can be used successfully to answer important questions in brain science.


Brain activity Cortex Electrophysiology Magnetic resonance Optical imaging brain imaging fMRI magnetic resonance spectroscopy physiology

Editors and affiliations

  • Fahmeed Hyder
    • 1
  1. 1.Yale UniversityNew HavenUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-934115-74-9
  • Online ISBN 978-1-59745-543-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site