Systems Biology

  • Ivan V. Maly

Part of the Methods in Molecular Biology book series (MIMB, volume 500)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Methods for Analyzing Biomolecular Systems

    1. Front Matter
      Pages 1-1
    2. Pedro Mendes, Stefan Hoops, Sven Sahle, Ralph Gauges, Joseph Dada, Ursula Kummer
      Pages 17-59
    3. Matthew A. Oberhardt, Arvind K. Chavali, Jason A. Papin
      Pages 61-80
    4. Clifford A. Shaffer, Jason W. Zwolak, Ranjit Randhawa, John J. Tyson
      Pages 81-111
    5. James R. Faeder, Michael L. Blinov, William S. Hlavacek
      Pages 113-167
  4. Spatial Analysis and Control of Cellular Processes

    1. Front Matter
      Pages 1-1
    2. C. Joanne Wang, Andre Levchenko
      Pages 203-219
    3. Bert J. Lao, Daniel T. Kamei
      Pages 221-236
    4. Jacob Czech, Markus Dittrich, Joel R. Stiles
      Pages 237-287
    5. Július Parulek, Miloš Šrámek, Michal Červęanský, Marta Novotová, Ivan Zahradník*
      Pages 289-312
    6. Justin Newberg, Juchang Hua, Robert F. Murphy
      Pages 313-332
  5. Methods for Larger-Scale Systems Analysis

    1. Front Matter
      Pages 1-1
    2. Mikhail K. Levin, Manju M. Hingorani, Raquell M. Holmes, Smita S. Patel, John H. Carson
      Pages 335-359
    3. Maciej H. Swat, Susan D. Hester, Ariel I. Balter, Randy W. Heiland, Benjamin L. Zaitlen, James A. Glazier
      Pages 361-428
    4. Shlomo Ta’asan, Rima Gandlin
      Pages 429-443
    5. Ali Navid, Cheol-Min Ghim, Andrew T. Fenley, Sooyeon Yoon, Sungmin Lee, Eivind Almaas
      Pages 469-494
  6. Back Matter
    Pages 495-500

About this book


The rapidly developing methods of systems biology can help investigators to make inference and predictions from their data that intuition alone would not discern; however, the difficulty lies in the broad knowledge of mathematics and engineering that seems to be required to even evaluate the applicability of the methods to the problem at hand. In Systems Biology, scientists who possess that mathematical knowledge and have applied it effectively to various biological problems contribute methods which reflect their experience, crystallized in a form very similar to typical biological laboratory protocols. In order to best aid researchers, the chapters supply the theory behind the method, its step-by-step implementation, and the pitfalls explained thoroughly and from the practical angle. As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Cutting-edge and easy to use, Systems Biology shatters the perceived insurmountable barrier between the laboratory and systems-biological research techniques.


Biomedical research Biomolecular systems Cellular processes Large scale systems Spatial analysis Termination biology genome methodology molecular biology

Editors and affiliations

  • Ivan V. Maly

There are no affiliations available

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-934115-64-0
  • Online ISBN 978-1-59745-525-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site