© 2007

Liver Immunology

Principles and Practice

  • M. Eric Gershwin
  • John M. Vierling
  • Michael P. Manns

Table of contents

  1. Front Matter
    Pages i-xv
  2. Contemporary Liver Immunology and Immunopathology

  3. Introduction

    1. Front Matter
      Pages 13-13
    2. Cliona O’Farrelly, Derek G. Doherty
      Pages 15-24
    3. Cliona O’Farrelly, Derek G. Doherty
      Pages 41-48
    4. Masanori Abe, Angus W. Thomson
      Pages 49-59
    5. James D. Gorham
      Pages 61-70
    6. Golo Ahlenstiel, Barbara Rehermann
      Pages 71-82
    7. Pietro Invernizzi, Ilaria Bianchi, Massimo Locati, Raffaella Bonecchi, Carlo Selmi
      Pages 83-93
    8. Wajahat Z. Mehal, Scott L. Friedman
      Pages 111-121
    9. Chen Liu, James M. Crawford
      Pages 123-136
    10. Christopher L. Bowlus
      Pages 137-149
  4. Bacterial, Parasitic, and Viral Infections of the Liver

    1. Front Matter
      Pages 151-151
    2. Valentina Medici, Lorenzo Rossaro, Sripriya Balasubramanian, Stuart H. Cohen
      Pages 153-162
    3. Johannes Hadem, Michael P. Manns
      Pages 163-177
    4. Antonio Bertoletti, Patrick Kennedy, Adam J. Gehring
      Pages 179-191
    5. Heiner Wedemeyer, Markus Cornberg, Michael P. Manns
      Pages 193-208
    6. Sven Pischke, Arndt Vogel, Elmar Jaeckel, Michael P. Manns
      Pages 209-217

About this book


Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with, among other things, the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, allograft rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. Immunology has various applications in several disciplines of science, and as such is further divided.

Liver Immunology: Principles and Practice covers bacterial, parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation in an easy-to-read and thorough format. Authors also address the key issues that have arisen in this field in recent years, including physiological roles of hepatocytes, sinusoidal lining cells, activated macrophages (Kupffer cells), cholangiocytes and stellate cells, and their modulation of T cells, natural killer (NK) cells and NKT cells. This volume will become a must-read for clinicians, investigators and students, novice and expert alike.


Antigen autoimmune disease bacteria cytokine diseases genetics hepatitis immunology infection infections liver liver disease parasite pathology transplantation

Editors and affiliations

  • M. Eric Gershwin
    • 1
  • John M. Vierling
    • 2
  • Michael P. Manns
    • 3
  1. 1.Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California at Davis School of MedicineDavis
  2. 2.Departments of Medicine and Surgery Baylor Liver HealthBaylor College of MedicineHouston
  3. 3.Department of Gastroenterology, Hepatology, and EndocrinologyMedical School of HannoverHannoverGermany

Bibliographic information

  • Book Title Liver Immunology
  • Book Subtitle Principles and Practice
  • Editors M. Eric Gershwin
    John M. Vierling
    Michael P. Manns
  • DOI
  • Copyright Information Humana Press Inc. 2007
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-58829-818-8
  • eBook ISBN 978-1-59745-518-3
  • Edition Number 1
  • Number of Pages XV, 486
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Hepatology
    Internal Medicine
  • Buy this book on publisher's site


From the reviews:

"We enjoyed reading this book because it contains much useful information and many interesting insights into liver immunology. The topic is of great interest because of continuing advances in our understanding of chronic viral infection of the liver, autoimmune liver disease, and liver transplantation. … In summary, this book is a good attempt to provide broad coverage of liver immunology … ." (Gideon Hirschfield and Jenny Heathcote, New England Journal of Medicine, April, 2008)

"This book summarises the latest research on liver pathology and pathophysiology. … There is an abundance of figures and tables, which are easy to understand, and a wide illustration of clinical applications that have been described in great detail. On the whole this is a very attractive book for students and medics who seek a comprehensive introduction into liver immunology and an update of the latest proceedings in clinical and translational research. I can therefore easily recommend this book for all liver enthusiasts." (York Aarbodem, Immunology News, November, 2008)