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The GABA Receptors

  • S. J. Enna
  • Hanns Möhler

Part of the The Receptors book series (REC)

Table of contents

  1. Front Matter
    Pages i-x
  2. S. J. Enna
    Pages 1-21
  3. Robert L. Macdonald, Jing-Qiong Kang, Martin J. Gallagher, Hua-Jun Feng
    Pages 111-142
  4. James K. Rowlett, Angela N. Duke, Donna M. Platt
    Pages 143-168
  5. David H. Farb, Janine L. Steiger, Stella C. Martin, Maria C. Gravielle, Terrell T. Gibbs, Shelley J. Russek
    Pages 169-238
  6. Wolfgang Froestl, Nigel G. Cooke, Stuart J. Mickel
    Pages 239-251
  7. Andrés Couve, Stephen J. Moss, Menelas N. Pangalos
    Pages 253-271
  8. Jim Yu-Hsiang Tiao, Bernhard Bettler
    Pages 273-287
  9. Norman G. Bowery
    Pages 289-312
  10. Back Matter
    Pages 313-325

About this book

Introduction

This volume is the third edition of a monograph series that was first published in 1983. The demand for this work is a testament to the impact of studies on -aminobutyric acid (GABA) receptors on the basic understanding of synaptic transmission and on defining the clinical importance of the neurotransmitter system. Chronicled in The GABA Receptors, Third Edition, are the advances made in understanding the molecular and pharmacological properties of GABA A and GABA receptors since the topic was last reviewed in 1996. Particular B emphasis is placed on describing the assembly, structure, and function of GABA B sites, the first heterodimeric G protein-coupled receptors identified in vivo. In addition, there are reports dealing with the subunit composition, trafficking, and pharmacological selectivity of GABA receptors. Aside from providing A insights into the fundamental properties of ligand-gated ion channels and second messenger systems, the findings detailed in this work point the way for developing novel therapeutics capable of more selectively manipulating these transmitter sites.

Keywords

Activation Endoplasmatisches Reticulum Epilepsie autism spectrum disorder gene expression genes regulation

Editors and affiliations

  • S. J. Enna
    • 1
  • Hanns Möhler
    • 2
    • 3
  1. 1.Departments of Molecular and Integrative Physiology and of Pharmcology, Toxicology and TherapeuticsUniversity of KansasKansas City
  2. 2.Department of Chemistry and Applied Biosciecnes Swiss Federal Institute of Technology (ETH)Institute of Pharmacology University of ZurichZurich
  3. 3.Collegium HelveticumZurichSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-465-0
  • Copyright Information Humana Press Inc. 2007
  • Publisher Name Humana Press
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-58829-813-3
  • Online ISBN 978-1-59745-465-0
  • Series Print ISSN 1048-6909
  • Series Online ISSN 2524-6488
  • Buy this book on publisher's site