Oxidative Stress in Aging

From Model Systems to Human Diseases

  • Satomi Miwa
  • Kenneth B. Beckman
  • Florian L. Muller

Part of the Aging Medicine book series (AGME)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Introduction

    1. Satomi Miwa, Florian L. Muller, Kenneth B. Beckman
      Pages 3-10
    2. Satomi Miwa, Florian L. Muller, Kenneth B. Beckman
      Pages 11-35
  3. The Role of Oxidative Stress in Aging

    1. Different Model Systems

      1. João F. Passos, Thomas von Zglinicki
        Pages 39-52
      2. Stavros Gonidakis, Valter D. Longo
        Pages 67-79
      3. Robin J. Mockett, Rajindar S. Sohal, William C. Orr
        Pages 111-128
      4. Florian L. Muller
        Pages 129-146
    2. The Comparative Approach

  4. Oxidative Stress in Human Aging and Diseases

    1. Muhammad A. Abdul-Ghani, Ralph A. DeFronzo
      Pages 191-211
    2. Jeffrey A. Stuart, Melissa M. Page
      Pages 213-228
    3. Sean P. Didion, Sophocles Chrissobolis, Frank M. Faraci
      Pages 229-251
    4. Paul S. Brookes, David L. Hoffman
      Pages 253-267
  5. Future

    1. Ilsa I. Rovira, Toren Finkel
      Pages 293-307
    2. Satomi Miwa, Florian L. Muller, Kenneth B. Beckman
      Pages 309-312
  6. Back Matter
    Pages 313-320

About this book


Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals).  Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause.  Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions.  Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation.  In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed.


Alzheimer Diabetes Diabetes mellitus aging biochemistry cancer senescence

Editors and affiliations

  • Satomi Miwa
    • 1
  • Kenneth B. Beckman
    • 2
  • Florian L. Muller
    • 3
  1. 1.Institute for Ageing and HealthNewcastle UniversityNewcastle upon TyneUK
  2. 2.Functional Genomics CoreChildren's Hospital Oakland Research InstituteOaklandUSA
  3. 3.Department of Cellular and Structural BiologyUniversity of Texas Health Science Center at San AntonioSan AntonioUSA

Bibliographic information