Arthritis Research

Methods and Protocols Volume 2

  • Andrew P. Cope

Part of the Methods in Molecular Medicine book series (MIMM, volume 136)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Immunobiology

    1. Front Matter
      Pages 1-1
    2. Henrik E. Mei, Taketoshi Yoshida, Gwendolin Muehlinghaus, Falk Hiepe, Thomas Dörner, Andreas Radbruch et al.
      Pages 3-18
    3. Marie Wahren-Herlenius, Stina Salomonsson
      Pages 19-24
    4. Hye-Jung Kim, Claudia Berek
      Pages 25-37
    5. John A. Gebe, William W. Kwok
      Pages 39-50
    6. Clare Alexander, Richard C. Duggleby, Jane C. Goodall, Malgosia K. Matyszak, Natasha Telyatnikova, J. S. Hill Gaston
      Pages 51-68
    7. Eva Koffeman, Elissa Keogh, Mark Klein, Berent Prakken, Salvatore Albani
      Pages 69-86
    8. Alla Skapenko, Hendrik Schulze-Koops
      Pages 87-96
    9. Lucy R. Wedderburn, Douglas J. King
      Pages 97-116
    10. Karim Raza, Dagmar Scheel-Toellner, Janet M. Lord, Arne N. Akbar, Christopher D. Buckley, Mike Salmon
      Pages 117-138
    11. Danielle Burger, Jean-Michel Dayer
      Pages 139-148
    12. Nicola Dalbeth, Margaret F. C. Callan
      Pages 149-163
    13. Allison R. Pettit, Lois Cavanagh, Amanda Boyce, Jagadish Padmanabha, Judy Peng, Ranjeny Thomas
      Pages 165-181
  3. Animal Models of Arthritis

    1. Front Matter
      Pages 183-183
    2. Richard O. Williams
      Pages 191-199
    3. Marie M. Griffiths, Grant W. Cannon, Tim Corsi, Van Reese, Kandie Kunzler
      Pages 201-214
    4. Kutty Selva Nandakumar, Rikard Holmdahl
      Pages 215-223
    5. Stefan Carlsen, Shemin Lu, Rikard Holmdahl
      Pages 225-242
    6. Wim B. van den Berg, Leo A. B. Joosten, Peter L. E. M. van Lent
      Pages 243-253
    7. Peter Olofsson, Rikard Holmdahl
      Pages 255-268
    8. Paul Monach, Kimie Hattori, Haochu Huang, Elzbieta Hyatt, Jody Morse, Linh Nguyen et al.
      Pages 269-282
    9. Anna-Marja Säämänen, Mika Hyttinen, Eero Vuorio
      Pages 283-302
  4. Application of New Technologies to Define Novel Therapeutic Targets

    1. Front Matter
      Pages 303-303
    2. Tineke C. T. M. van der Pouw Kraan, Lisa G. M. van Baarsen, François Rustenburg, Belinda Baltus, Mike Fero, Cornelis L. Verweij
      Pages 305-327
    3. Monika Hermansson, Jeremy Saklatvala, Robin Wait
      Pages 349-359
    4. Matthew J. Peirce, Jeremy Saklatvala, Andrew P. Cope, Robin Wait
      Pages 361-367
    5. Alison Davis, Corinne Taylor, Kate Willetts, Clive Smith, Brian M. J. Foxwell
      Pages 395-419
  5. Back Matter
    Pages 421-435

About this book


Arthritis Research: Methods and Protocols is a compendium of data pertinent to the methods and protocols that have contributed to recent advances in molecular medicine in general, but to the molecular basis of rheumatic disease in particular. These volumes details novel technologies, some of which are still evolving and whose impacts are yet to be determined. Leaders in the field contribute to cover such exciting and cutting edge topics as imaging and immunohistochemistry, analysis of cartilage and bone catabolism, immunobiology, and cell trafficking.

In Volume 1, authors discuss synovial joint morphology, histopathology, and immunohistochemistry, cartilage matrix and bone biology, and cell trafficking, migration and invasion. Volume 2 is broken up into sections that cover immunobiology and T cells, animal models of arthritis, and applications of new technologies, such as Differential Display Reverse Transcription-Polymerase Chain Reaction (DDRT-PCR), to define novel therapeutic targets. Both volumes combine to produce a concise set of protocols condensing decades of experience and expertise.

Arthritis Research: Methods and Protocols will be a valuable tool for basic research investigators, clinician scientists, pathologists, immunologists, and biochemists looking to stay current in their fields.


Arthritis PCR Vivo gene expression genes macrophage function migration signal transduction tissue transcription

Editors and affiliations

  • Andrew P. Cope
    • 1
  1. 1.The Kennedy Institute of RheumatologyImperial College LondonLondonUK

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-918-5
  • Online ISBN 978-1-59745-402-5
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • Buy this book on publisher's site