Overview
- Comprehensive, state-of-the-art review of rare lung diseases
- Thoroughly sheds light on the molecular mechanisms that evoke the clinical presentation and engender treatment strategies for each rare lung disease
- Covers all aspects of such disorders as pulmonary alveolar proteinosis (PAP), pulmonary alveolar microlithiasis (PAM), inherited disorders of surfactant metabolism, and pulmonary arterial hypertension, to name just several
- Includes supplementary material: sn.pub/extras
Part of the book series: Respiratory Medicine (RM)
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Table of contents (19 chapters)
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Back Matter
Keywords
About this book
The study of rare lung disorders enhances our understanding of common pulmonary diseases such as fibrosis and emphysema. Molecular Basis of Pulmonary Disease: Insights from Rare Lung Disorders brings together a panel of distinguished clinicians and molecular scientists who are experts in a range of rare lung diseases and their underlying molecular defects. Each chapter focuses on the pathogenic mechanisms and therapeutic targets suggested by basic research and follows an easy-to-read format: brief introduction followed by discussion of epidemiology, genetic basis and molecular pathogenesis, animal models, clinical presentation, diagnostic approaches, conventional management and treatment strategies, as well as future therapeutic targets and directions. Disorders ranging from the Marfan and Goodpasture’s syndromes to Sarcoidosis and alpha one antitrypsin deficiency are treated in detail. Written for pulmonary clinicians and scientists alike, Molecular Basis of Pulmonary Disease: Insights from Rare Lung Disorders is a comprehensive and invaluable nesource that sheds new light on the molecular mechanisms influencing the clinical presentation and treatment strategies for these debilitating disorders.
Reviews
From the reviews:
“This unique book attempts to briefly review the clinical manifestations and evolution of a few uncommon, mostly very rare pulmonary disorders, some of which even subspecialist pulmonologists rarely or never encounter during their careers. … The editors derive insight and input from contributors of eclectic knowledge and experience. … Certainly, the audience would be limited to basic scientists and a modicum of clinicians with unique interests. … The book achieves its likely intended goals well. … a potentially useful addition to my medical library.” (Joel C. Seidman, Doody’s Review Service, July, 2010)Editors and Affiliations
Bibliographic Information
Book Title: Molecular Basis of Pulmonary Disease
Book Subtitle: Insights from Rare Lung Disorders
Editors: Francis X. McCormack, Ralph J. Panos, Bruce C. Trapnell
Series Title: Respiratory Medicine
DOI: https://doi.org/10.1007/978-1-59745-384-4
Publisher: Humana Totowa, NJ
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media, LLC 2010
Hardcover ISBN: 978-1-58829-963-5Published: 19 March 2010
Softcover ISBN: 978-1-4939-6081-1Published: 23 August 2016
eBook ISBN: 978-1-59745-384-4Published: 10 March 2010
Series ISSN: 2197-7372
Series E-ISSN: 2197-7380
Edition Number: 1
Number of Pages: XI, 438
Topics: Pneumology/Respiratory System