Transforming Growth Factor-β in Cancer Therapy, Volume I

Basic and Clinical Biology

  • Sonia B. Jakowlew

Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Basic Concepts of TGF-β Signaling in Normal Physiology and Cancer Pathobiology

    1. Front Matter
      Pages 1-1
    2. Vesna Todorovic, Daniel B. Rifkin
      Pages 37-55
    3. Marko Hyytiäinen, Katri Koli, Jorma Keski-Oja
      Pages 57-75
    4. Azeddine Atfi, Marie-Francoise Bourgeade
      Pages 77-90
    5. Qunyan Jin, Guofeng Gao, Kathleen M. Mulder
      Pages 169-184
    6. Tae-Aug Kim, Seong-Jin Kim
      Pages 199-211
    7. Leslie I. Gold, Jon Lecanda
      Pages 213-242
    8. Arja Band, Marikki Laiho
      Pages 243-257
    9. Sylvie Thuault, Ulrich Valcourt, Marcin Kowanetz, Aristidis Moustakas
      Pages 259-273
    10. Christina H. Stuelten, Anita B. Roberts, William G. Stetler-Stevenson
      Pages 275-292
    11. Irwin M. Liu, Stephen H. Schilling, Xiao-Fan Wang
      Pages 293-303

About this book


Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. Part I presents basic concepts of transforming growth factor-ß signaling in normal physiology and cancer pathobiology. Part II investigates transforming growth factor-ß superfamily members in normal and tumor biology. Part III details transforming growth factor-ß in inflammation and fibrosis.

This volume’s companion, Cancer Treatment and Therapy, examines transforming growth factor-ß in several developing and advanced cancers and discusses methods of treatment and therapy. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment.


Carcinom biological functions gene therapy genes physiology signal transduction transcription

Authors and affiliations

  • Sonia B. Jakowlew
    • 1
  1. 1.Cancer Training Branch, Office of Centers, Training and ResourcesNational Cancer InstituteBethesda

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-58829-714-3
  • Online ISBN 978-1-59745-292-2
  • About this book