Opiate Receptors and Antagonists

From Bench to Clinic

  • Reginald L. DeanIII
  • Edward J. Bilsky
  • S. Stevens Negus
Part of the Contemporary Neuroscience book series (CNEURO)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Opioid Receptors

    1. Lindsay H. Burns, Todd W. Vanderah, Hoau-Yan Wang
      Pages 3-17
    2. Ellen M. Unterwald, Richard D. Howells
      Pages 19-44
    3. Mark K. Greenwald, Caren L. Steinmiller
      Pages 45-65
    4. Jonathan Moorman, Zhi Qiang Yao, Edward J. Bilsky, Deling Yin
      Pages 67-80
  3. Opioid Antagonists: Chemistry and Pharmacology

    1. Jean M. Bidlack, Jennifer L. Mathews
      Pages 83-97
    2. Cécile Béguin, Bruce M. Cohen
      Pages 99-118
    3. Beatriz Fioravanti, Todd W. Vanderah
      Pages 119-136
    4. Richard B. Rothman, Subramaniam Ananthan, Edward J. Bilsky
      Pages 137-151
    5. Chun-Su Yuan, Robert J. Israel
      Pages 175-198
  4. Substance Abuse

    1. Kevin A. Sevarino, Thomas R. Kosten
      Pages 227-245
    2. Lindsay H. Burns, Francesco Leri, Mary C. Olmstead
      Pages 247-261
    3. B. Le Foll, Zuzana Justinova, G. Tanda, Marcello Solinas, Peter Selby, Steven R. Goldberg
      Pages 299-314
    4. Andrea King, Rachel Torello, Suchitra Krishnan-Sarin, Stephanie O'Malley
      Pages 315-332
  5. Alcohol and Ingestive Behaviors

About this book

Introduction

The evolution in our understanding of Opioid receptors and their subtypes is intimately linked to the development of new pharmacological treatments for diseases and disorders as diverse as addiction, self-injurious behavior, pain, cancer, inflammation, eating disorders, traumatic injury, pruritis and movement disorders. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent efforts from leading international scientists and clinicians making use of the latest information emerging from the study of the opioid-receptor system. The authors use a variety of experimental and clinical approaches involving the fields of molecular biology, biochemistry, anatomy, pharmacology, behavioral neuroscience and psychiatry to illustrate rapidly developing experimental and therapeutic areas. Highlights include characterization of opioid receptors, chemistry and pharmacology of opiod antagonists for various receptor subtypes (Mu, Kappa, and Delta), discussion of therapeutic uses of opiod antagonists and exploration of innovative approaches to therapeutic drug delivery.

Opioid Receptors and Antagonists: From Bench to Clinic offers a comprehensive view of recent work on opiod antagonist applications and uses in various clinical treatments. Emphasis is placed on disorders of the reward system. This volume serves as reference while also illuminating prospects for future research.

Keywords

Antag Antagonists Bench Clinic Contemporary Dean Ethanol Neuroscience Opiate Opioid Receptors marijuana

Editors and affiliations

  • Reginald L. DeanIII
    • 1
  • Edward J. Bilsky
    • 2
  • S. Stevens Negus
    • 3
  1. 1.Life Sciences/ToxicologyAlkermes, Inc.CambridgeUSA
  2. 2.Department of Pharmacology, College of Osteopathic MedicineUniversity of New EnglandBiddlefordUSA
  3. 3.Department of Pharmacology and ToxicologyVirginia Commonwealth UniversityRichmondUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-197-0
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-58829-881-2
  • Online ISBN 978-1-59745-197-0
  • About this book