The Genetics of Male Infertility

  • Douglas T. Carrell

Table of contents

  1. Front Matter
    Pages i-xv
  2. Methods and Tools for the Study

    1. Front Matter
      Pages 2-2
    2. Adrian E. Platts, David J. Dix, Stephen A. Krawetz
      Pages 37-54
    3. Honghua Li, Xiangfeng Cui, Danielle M. Greenawalt, Guohong Hu, Nyam-Osor Chimge, Sreemanta Pramanik et al.
      Pages 55-76
    4. Sarah J. Conner, Linda Lefièvre, Jackson Kirkman-Brown, Gisela S. M. Machado-Oliveira, Frank Michelangeli, Stephen J. Publicover et al.
      Pages 77-97
    5. Angshumoy Roy, Yi-Nan Lin, Martin M. Matzuk
      Pages 99-111
  3. Meiosis and Errors of Meiosis

    1. Front Matter
      Pages 113-113
    2. Daniel Topping, Petrice Brown, Terry Hassold
      Pages 115-128
    3. Renee H. Martin
      Pages 129-144
    4. Francesca K. E. Gordon, Dolores J. Lamb
      Pages 145-163
  4. The Y Chromosome, Development Spermatogenesis, and Sperm Maturation

    1. Front Matter
      Pages 165-165
    2. Mark S. Fox, Renee A. Reijo Pera
      Pages 167-184
    3. Alexander I. Agoulnik, Shu Feng
      Pages 185-198
    4. Martti Parvinen, Noora Kotaja, Durga Prasad Mishra, Paolo Sassone-Corsi
      Pages 199-209
    5. Gail A. Cornwall, Hans H. von Horsten
      Pages 211-231
  5. Clinical Applications of the Study of the Genetics of Male Infertility

    1. Front Matter
      Pages 232-232
    2. Leslie Ayensu-Coker, Colin Bishop, Jan Rohozinski
      Pages 233-238
    3. Ken McElreavey, Celia Ravel, Brahim El Houate, Jacqueline Mandelbaum, Sandra Chantot-Bastaraud, Jean-Pierre Siffroi
      Pages 239-249

About this book

Introduction

Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.
This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms.
Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

Keywords

Chromosom DNA Genetic abnormalities In silico technologies In vitro fertilization Intracytoplasmic injection SNP Single Nucleotide Polymorphism Termination genetics infertility transcription translation

Editors and affiliations

  • Douglas T. Carrell
    • 1
  1. 1.Departments of Surgery (Urology), Obstetrics and Gynecology, and PhysiologyUniversity of Utah School of MedicineSalt Lake City

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-176-5
  • Copyright Information Humana Press Inc. 2007
  • Publisher Name Humana Press
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-58829-863-8
  • Online ISBN 978-1-59745-176-5
  • About this book