Cancer Proteomics

From Bench to Bedside

  • Sayed S. Daoud

Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Proteomics Technologies

    1. Front Matter
      Pages 1-1
    2. Belinda Willard, Suma Kaveti, Michael T. Kinter
      Pages 3-35
  3. Cell Signaling Proteomics

    1. Front Matter
      Pages 37-37
    2. Kyunghee Lee, Tao Wang, Abdur Rehman, Yuhua Wang, Sayed S. Daoud
      Pages 39-57
  4. Tumor Proteomics

    1. Front Matter
      Pages 79-79
    2. Christina M. Annunziata, Dana M. Roque, Nilofer Azad, Elise C. Kohn
      Pages 101-120
    3. Cecilia Sarto, Vanessa Proserpio, Fulvio Magni, Paolo Mocarelli
      Pages 121-137
    4. M.A. Reymond, M. Beshay, H. Lippert
      Pages 139-159
    5. Nils Brünner, Mads Holten-Andersen, Fred Sweep, John Foekens, Manfred Schmitt, Michael J. Duffy
      Pages 189-207
  5. Bioinformatics and Regulatory Aspects of Proteomics

    1. Front Matter
      Pages 209-209
    2. Rolf Apweiler, Michael Mueller
      Pages 211-235
    3. Dave Li, Joseph Hackett, Maria Chan, Gene Pennello, Steve Gutman
      Pages 237-258
  6. Back Matter
    Pages 259-264

About this book

Introduction

Over the past 20 years or so, there have been tremendous advances in our understanding of how normal cells transform to cancer and the importance of signaling pathways in cancer initiation and progression. Therefore, proteomics technologies must be improved for more global analysis of protein content of cells, tissues and body fluids as well as the posttranslational modifications to allow for proper detections and validation. In Cancer Proteomics, the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.

Keywords

Bioinformatics Cancer Research Carcinom Oncology Proteomics Translation classification diagnostics proteins

Editors and affiliations

  • Sayed S. Daoud
    • 1
  1. 1.Department of Pharmaceutical SciencesWashington State UniversityPullman

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-169-7
  • Copyright Information Humana Press Inc. 2008
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-58829-858-4
  • Online ISBN 978-1-59745-169-7
  • About this book